Outcome of Cardiac Arrest Patients Following Guidelines Implementation Over the Years
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cardiac Arrest. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Implementation of the New Guidelines on the Management of Patients Resuscitated From Cardiac Arrest and Impact on Survival: a Multicenter Retrospective Observational Study
Overview
The study aims to evaluate the level of local implementation of the new interventions introduced by the guidelines for post-cardiac arrest management and their impact on the survival of patients resuscitated from cardiac arrest and admitted to intensive care over a 14-year period. During this time period, the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) introduced three new guidelines for post-cardiac arrest management, each five years apart: the 2010, 2015, and 2021 guidelines.
Detailed description
This study is a retrospective multicenter cohort observational study (two centers involved: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico and Fondazione IRCCS San Gerardo dei Tintori).
All patients admitted to the Intensive Care Units (ICU) of the hospitals involved in the study from January 1, 2011, to May 30, 2024, following cardiac arrest of any etiology, who meet the inclusion and exclusion criteria, will be enrolled.
Primary outcome measures
- Intensive Care Unit (ICU) Survival [Time frame: From cardiac arrest date to ICU discharge or death, up to 90 days]
- Neurological recovery at ICU discharge [Time frame: From cardiac arrest date to ICU discharge or death, up to 90 days]
Secondary outcome measures (1)
- Hospital discharge status [Time frame: From cardiac arrest date to hospital discharge or death, up to 180 days]
Eligibility criteria
Inclusion criteria
- Patients resuscitated from cardiac arrest and admitted to intensive care unit
- Age ≥ 18 years
- Out-of-hospital and in-hospital cardiac arrest
- Cardiac arrest of any etiology
Exclusion criteria
- Pediatric patients (<18 years)
- Patients not admitted to one of the aforementioned intensive care units.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Italy · 2 centers
- Fondazione IRCCS San Gerardo dei Tintori — Monza
- IRCCS Ca' Granda Ospedale Maggiore Policlinico — Milan
Identifiers
NCT: NCT06608771 · 5033