Menu
Recruiting NCT06607887

The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy

Phase IV Interventional Infection Wound Antibiotic Resistant Infection

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: IV antibiotic, Oral antibiotic.
Who it may be relevant to
Registry conditions: Infection Wound, Antibiotic Resistant Infection. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

Comparison between postoperative parenteral prophylactic antibiotics, and oral antibiotics regarding the incidence of post laparoscopic cholecystectomy infection.

Interventions

  • Drug IV antibiotic
    Parenteral prophylactic antibiotics (cefazolin), 1st dose at the time of induction of anesthesia, 2nd dose after 12hs from the surgery.
  • Drug Oral antibiotic
    Parenteral prophylactic antibiotic (cefazolin), dose at the time of induction of anesthesia and then oral antibiotic for five days postoperative.

Primary outcome measures

  • Surgical site infection [Time frame: 4 weeks]
Secondary outcome measures (3)
  • Fever [Time frame: 4 weeks]
  • Length of the hospital stay [Time frame: 4 weeks]
  • Hematoma and Seroma formation [Time frame: 4 weeks]

Eligibility criteria

Inclusion criteria

  • Adult patients (aged above 18 years) undergoing laparoscopic cholecystectomy.

Exclusion criteria

  • patients with comorbidities (Diabetes, malignancies, Immunosuppressed). Lost of follow-up. Patients received antibiotics within 72 hr before admission. Complicated cases involved, gangrenous and perforated cholecystitis and abscess.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Prevention

Study locations

Egypt · 1 center
  • Minia University Hospital — Minya

Identifiers

NCT: NCT06607887 · Antibiotic77

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗