Effects of Resistance-band Training and Creatine and Whey Protein

Official title

Effects of Resistance-band Training and Nutritional Supplementation in Healthy Older Adults

Overview

The primary purpose of this research is to compare the effects of creatine monohydrate and/or whey protein supplementation during the first 10 weeks of a 20-week resistance-band training program on measures of body composition (whole-body lean tissue mass, total body water), arm and leg muscle thickness, upper- and lower-body muscle performance (i.e., strength, endurance) and functional ability (walking speed, balance). A secondary purpose of this research is to examine the effects of supplementation cessation (i.e., no creatine and/or whey protein supplementation) during the final 10 weeks of the 20-week resistance-band training program on these measures.

Detailed description

Sarcopenia, characterized by the age-related reduction in strength, muscle mass, and physical function, decreases the ability to perform activities of daily living. Physical inactivity and inadequate nutrition are contributing factors to the development of sarcopenia. Resistance training is a safe, viable and effective intervention which increases measures of muscle and bone mass, muscle performance (i.e., strength, endurance) and functional ability in older adults. However, older adults indicate that high costs and difficulty finding training programming and/or facilities are barriers to participating in resistance training. Home-based resistance-band training is safe, effective and serves as a viable alternative to traditional resistance training (i.e., involving free-weights and machine-based equipment). From a healthy aging perspective, resistance-band training elicits similar improvements in strength (primary indicator of sarcopenia) and functional ability compared to traditional resistance training in older adults. In addition to resistance training (involving resistance-bands), creatine and whey protein supplementations have also been shown to have favorable effects on measures of muscle, bone and functional ability in older adults. However, no study has examined the effects of resistance-band training and creatine and whey protein supplementation in older adults.

Interventions

• Dietary supplement Creatine Whey Protein
  3 grams creatine + 30 grams whey protein
• Dietary supplement Whey Protein
  30 grams Whey Protein

Primary outcome measures

• Whole-body lean mass (kg) [Time frame: baseline, week 10, week 20]
• Strength (kg) [Time frame: baseline, week 10, week 20]
• Endurance (number of repetitions to fatigue) [Time frame: baseline, week 10, week 20]
• Balance (Centre of Pressure) [Time frame: baseline, week 10, week 20]
• Hydration (kg) [Time frame: baseline, week 10, week 20]
• Gait Speed (meters) [Time frame: baseline, week 10, week 20]
• Muscle Hypertrophy (cm) [Time frame: baseline, week 10, week 20]

Eligibility criteria

Inclusion criteria

• Untrained (defined as those performing ≤ 1 resistance training session per week for ≥ 6 weeks prior to the start of the study)

Exclusion criteria

• Taking creatine monohydrate within 30 days prior to the start of the study
• Currently ingesting whey protein
• Have pre-existing allergies to latex, fruit, dairy, nuts, seafood and mustard

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation

Randomized

Model

Parallel assignment

Masking

Triple blind

Primary purpose

Treatment

Study locations

Canada · 1 center

• University of Regina — Regina

Identifiers

NCT: NCT06606717 · 825

Primary sources (government registries)

• ClinicalTrials.gov (US NIH)

View this study on ClinicalTrials.gov ↗