Effects of Resistance-band Training and Creatine Supplementation Strategies in Healthy Older Adults
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Creatine Bolus 5, Creatine Bolus 3, Creatine Intermittent 5, Placebo.
- Who it may be relevant to
- Registry conditions: Aging. Basic parameters: from 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Canada
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effects of Resistance-band Training and Creatine Supplementation in Healthy Older Adults
Overview
The primary purpose is to compare the effects of creatine supplementation (bolus ingestion of 5 grams vs. 3 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance). A secondary purpose of this research is to examine the effects of bolus ingestion of creatine (5 grams) compared to intermittent ingestion of creatine (2 x 2.5 grams) during 16 weeks of resistance-band training on measures of body composition (i.e., whole-body lean tissue mass, total body water), arm and leg muscle thickness (growth), muscle performance (i.e., power, strength, endurance) and functional ability (i.e., walking speed, balance).
Detailed description
Resistance-band training is safe, conveient, easy-to-use, eliminates potential barriers to exercise participation (i.e., lack of transportation to and from commercial training facilities) and results in high exercise compliance and adherence. Further, resistance-band training results in similar improvements in muscle performance and functional ability compared to traditional resistance-type training using free-weights and machines.
Creatine is a naturally occurring nitrogen-containing compound produced in the body in the liver and brain and can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products.
Evidence-based research shows that creatine supplementation, when ingested during a resistance exercise training program, improves measures of lean mass and muscle growth, muscle performance and functional ability. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.
Interventions
- Dietary supplement Creatine Bolus 5
(Serving 1: 5 grams of creatine + 3 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1). - Dietary supplement Creatine Bolus 3
(Serving 1: 3 grams of creatine + 5 grams of placebo in the morning; Serving 2: 8 grams of placebo at least 6 hours after Serving 1). - Dietary supplement Creatine Intermittent 5
(Serving 1: 2.5 grams of creatine + 5.5 grams of placebo in the morning, Serving 2: 2.5 grams of creatine + 5.5 grams of placebo at least 6 hours after Serving 1). - Dietary supplement Placebo
(Serving: 8 grams of placebo in the morning; Servings 2: 8 grams of placebo at least 6 hours after Serving 1).
Primary outcome measures
- Whole-body lean mass (kg) [Time frame: baseline, week 16]
- Muscle Hypertrophy (cm) [Time frame: baseline, week 16]
- Strength (kg) [Time frame: baseline, week 16]
- Endurance (number of repetitions to fatigue) [Time frame: baseline, week 16]
- Power (feet) [Time frame: baseline, week 16]
- Balance (Centre of Pressure) [Time frame: baseline, week 16]
- Gait Speed (meters) [Time frame: baseline, week 16]
Eligibility criteria
Inclusion criteria
- if you are 50 years of age and older
- if you have not been performing more than 1 resistance training session per week for the past 6 weeks or more.
Exclusion criteria
- if you have taken creatine supplements within 30 days prior to the start of the study
- if you have pre-existing allergies to the placebo (corn-starch maltodextrin).
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Treatment
Study locations
Canada · 1 center
- University of Regina — Regina
Identifiers
NCT: NCT06606704 · 853