Creatine Supplementation in Young Healthy Adults
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Creatine, Placebo.
- Who it may be relevant to
- Registry conditions: Improve Muscle Performance in Young Adults. Basic parameters: 18 years — 39 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Canada
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effects of Equal-volume Creatine Supplementation With Different Dosing Strategies on Body Composition and Muscle Performance in Young Healthy Adults
Overview
The purpose is to compare the effects of bolus ingestion (5 grams) vs. intermittent ingestion (2 x 2.5 grams) of creatine supplementation vs. placebo for 21 days on measures of body composition (lean tissue mass-indicator of muscle mass, total body water) and muscle performance (i.e., power, strength, endurance).
Detailed description
Creatine is a naturally occurring compound produced in the liver and brain. Creatine can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products (i.e. creatine supplementation).
Evidence-based research shows that creatine supplementation improves measures of body composition and muscle performance. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.
Interventions
- Dietary supplement Creatine
Creatine monohydrate - Dietary supplement Placebo
Maltodextrin
Primary outcome measures
- Whole-body lean mass (kg) [Time frame: baseline, day 21]
- Strength [Time frame: baseline, day 21]
- Endurance [Time frame: baseline, day 21]
- Hydration [Time frame: baseline, day 21]
- Power [Time frame: baseline, day 21]
- Power [Time frame: baseline, day 21]
Eligibility criteria
Inclusion criteria
- if you are 18-39 years of age
- if you have not been performing resistance training for at least 4 weeks prior to the start of the study.
Exclusion criteria
- if you are pregnant or nursing
- have taken creatine monohydrate within 30 days prior to the start of the study
- if you have pre-existing allergies to the placebo (corn-starch maltodextrin)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Treatment
Study locations
Canada · 1 center
- University of Regina — Regina
Identifiers
NCT: NCT06604793 · 834