Evaluation of Updated Procedure for Management of Refractory Out-of-hospital Cardiac Arrests
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: ECPR for out-of-hospital cardiac arrest.
- Who it may be relevant to
- Registry conditions: Cardiac Arrest, Out-Of-Hospital. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Evaluation of the Updated Procedure for the Management of Refractory Out-of-hospital Cardiac Arrests with SAMU 54 : the Revised ACEP Protocol in 02/2024
Overview
ECPR is a technique that has been rapidly developed in many cardiac arrest specialized centers In 2013, a specific management protocol was developed for patients in refractory out-of-hospital cardiac arrest around Nancy, France. To select patients with the best prognosis, the inclusion criteria defined were strict. This led to an over-selection of patients and a significant reduction in the number of eligible patients. A balance needed to be struck between over-selecting patients and maintaining the expertise of medical and paramedical teams in the field. In addition, it has also been shown that ECPR also increases the number of organs and transplants. In February 2024, the criteria for inclusion in the protocol were redefined to include any witnessed non-traumatic cardiac arrest, whatever the initial rhythm. This simplification should enable more patients to be included in the procedure. The aim of the study is to assess the patient's outcome
Interventions
- Other ECPR for out-of-hospital cardiac arrest
Patient with out-of-hospital cardiac arrest enrolled in the ECPR protocol
Primary outcome measures
- Survival [Time frame: 90 days after cardiac arrest]
Secondary outcome measures (2)
- Delays [Time frame: From event to implementation of ECMO, in minutes, Up to 180 minutes]
- Neurological outcome [Time frame: 30 days and 90 days after cardiac arrest]
Eligibility criteria
Inclusion criteria
- Out-of-hospital cardiac arrest
- enrolled in the ECPR program
- 18 years old or more
- Low-flow estimated <60minutes
Exclusion criteria
- traumatic cardiac arrest
- major comorbidities
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
France · 1 center
- CHRU — Nancy
Identifiers
NCT: NCT06603649 · 2024PI049