Menu
Not yet recruiting NCT06596070

Clinical Study of Intestinal Barrier Dysfunction After Gastrointestinal Surgery

— Observational Intestinal Barrier Dysfunction

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: No intervention was carried out.
Who it may be relevant to
Registry conditions: Intestinal Barrier Dysfunction. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Clinical Study of Intestinal Barrier Dysfunction in Patients After Gastrointestinal Surgery

Overview

The goal of this observational study is to explore the clinical influences associated with the development of intestinal barrier dysfunction in patients undergoing gastrointestinal surgery. The main question it aims to answer is:What clinical factors increase the probability of developing intestinal barrier dysfunction in patients after gastrointestinal surgery?

Interventions

  • Other No intervention was carried out
    This study is an observational study and no intervention was performed on the patients.

Primary outcome measures

  • operating time [Time frame: During surgery]
Secondary outcome measures (12)
  • nutritional status [Time frame: Preoperative]
  • bowel habit [Time frame: Preoperative]
  • Surgical Procedures [Time frame: During surgery]
  • hemorrhage [Time frame: During surgery]
  • Albumin [Time frame: Preoperative and postoperative 24 hours]
  • Infection indicators [Time frame: Preoperative and postoperative 24 hours]
  • age [Time frame: Preoperative]
  • gender [Time frame: Preoperative]
  • Body Mass Index [Time frame: Preoperative]
  • diabetes [Time frame: Preoperative]
  • enteral nutrition [Time frame: The average observation time is 2 weeks after surgery.]
  • Exhaust and defecation time [Time frame: The average observation time is one week after surgery]

Eligibility criteria

Inclusion criteria

  • men or women aged 18-80 years
  • expected feasible abdominal surgical treatment (partial gastrectomy, colorectal resection)
  • no preoperative intestinal barrier dysfunction
  • patients voluntarily participated in this study and signed an informed consent form.

Exclusion criteria

  • Patients or their families refused to participate in this study
  • chronic inflammatory diseases (e.g. inflammatory bowel disease, chronic hepatitis, chronic pancreatitis, chronic peptic ulcer, etc.)
  • history of antibiotic administration in the last 2 weeks
  • severe cognitive impairment and other inability to cooperate preoperative neoadjuvant radiotherapy
  • combined with severe hepatic, renal, and cardiac insufficiency patients.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-control

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT06596070 · PJ-2024-124

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗