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Not yet recruiting NCT06592469

Outcome of URS in Fresh Versus Recurrent Cases of Stone Ureter

Observational Stone Ureter

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Ureteroscopy.
Who it may be relevant to
Registry conditions: Stone Ureter. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Outcome of Ureteroscopy in Fresh Versus Recurrent Cases of Stone Ureter (Post-ESWL, Endoscopy, or Open Surgery)

Overview

Comparison of Ureteroscopy in fresh versus recurrent cases of stone ureter

Detailed description

Urolithiasis is a common cause of both urology outpatient clinic and emergency room encounters. Approximately 75-90% of ureteral stones pass spontaneously. from this point of view other managements of ureteric stones either ESWL, ureteroscopy or open surgery according to location, site, size, and density. Ureteroscopy is commonly used to diagnose and treat kidney and ureteral stones, ureteral strictures, and urothelial cancers. Semirigid URS is the gold standard of treatment for ureteral stones. High success rates and low morbidity have been reported in semirigid URS. but complications still occur in some cases. The possibility to predict their occurrence should influence patient advisement and better case selection. there are many predictors of successful URS as age, gender, previous ESWL, and stone character. In addition, the impacted stone is a risk factor, and it is described in the literature as ureteral wall thickness, higher grades of hydronephrosis, ureteral stricture, polyp, inflammatory reaction, and difficulty to introduce the guide wire. the literature is very poor in illustrating the previous procedures as a predictor of successful URS only seen in very few original articles as second-time URS after any procedure decreases the rate of success, so it is a point of research that Amr Moustafa aims to clarify. Amr Moustafa will conduct a prospective study to evaluate the outcomes of URS for stones in the fresh and recurrent cases.

Interventions

  • Procedure Ureteroscopy
    URS is done to each group to reveal outcome of stone free rate in fresh versus recurrent cases of stone ureter

Primary outcome measures

  • Stone free rate of Urereroscopy in fresh versus recurrent cases of stone ureter [Time frame: 1 day post operative by MSCTKUB or Plain KUB to determine residual stones post operative]
Secondary outcome measures (3)
  • • Rate of intraoperative findings in each group. [Time frame: Intraoperative]
  • • The rate of complication in each group [Time frame: Intraoperative by ureteroscope and one day post operative by MSCT]
  • • The rate of stone impaction in each group [Time frame: Intraoperative by ureteroscope]

Eligibility criteria

Inclusion criteria

  • • all cases with middle and lower ureteric stone candidate for endoscopy.
  • Stone 15mm or less.

Exclusion criteria

  • • Patients with a ureteral stent.
  • Patient refusing participation.
  • Pregnant woman.
  • Active urinary tract infection.
  • Comorbidities prevent intervention including bleeding tendency or uncorrectable coagulation profile.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Egypt · 1 center
  • Faculty of Medicine Assiut University — Asyut

Identifiers

NCT: NCT06592469 · Outcome of Ureteroscopy

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗