Cognitive-motor Training in Parkinson Disease
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Cognitive-motor training, Conventional physiotherapy.
- Who it may be relevant to
- Registry conditions: Parkinson Disease. Basic parameters: 40 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Taiwan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Cognitive-motor Training on Brain Activity, Cognitive Function, and Walking Ability in People With Parkinson Disease
Overview
Literature reviews showed the cognitive-motor training that combines cognitive tasks may enhance cognitive functions more effectively than individual interventions. Stepping-based cognitive-motor training has been shown to improve cognitive functions, balance, and gait performance in older adults. However, there is insufficient research evidence on the impact and correlation of this training mode on the walking ability, executive functions, and brain activity changes in people with PD. Therefore, this study is designed to investigate the effects of stepping-based cognitive-motor training on the walking ability, executive functions, and brain activity in people with PD.
Interventions
- Other Cognitive-motor training
Cognitive-motor training is that cognitive tasks incorporated into motor tasks. - Other Conventional physiotherapy
Conventional physiotherapy includes stretching, ROM exercise, strengthening exercise, and eye-hand coordination.
Primary outcome measures
- Gait variability [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Gait speed [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Step length [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Step width [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Single support time [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Double support time [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Frontal Assessment Battery [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Stroop color and word test [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Digit span test [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Event-related potential - N2 [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
Secondary outcome measures (4)
- Mini-Balance Evaluation Systems Test [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Montreal Cognitive Assessment [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Timed up and go test [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
- Parkinson Disease Questionnaire [Time frame: Before and after 8 weeks of intervention, as well as 4 weeks after intervention]
Eligibility criteria
Inclusion criteria
- Diagnoses of idiopathic Parkinson disease
- Stable dopaminergic medicine ≥ 2 weeks
- Able to walk 10 meters without aid
- Mini-Mental Status Examination ≥ 24 points
- No uncorrected visual or auditory disorders
- Education at least junior high school
- No other disease may affect balance
Exclusion criteria
- Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders
- History of brain surgery (e.g. deep brain stimulation)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Taiwan · 1 center
- National Yang Ming Chiao Tung University — Taipei
Identifiers
NCT: NCT06588439 · NYCU113006AF2