Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: RGD, Xenograft, Split crest technique.
- Who it may be relevant to
- Registry conditions: Implant Dentistry. Basic parameters: 18 years — 30 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement. A Randomized Clinical Trial
Overview
The aim of the present study is to evaluate the efficacy of xenograft alone or xenograft mixed with Arginylglycylaspartic acid (RGD) , in horizontal ridge augmentation with split-crest technique, for implant placement.
Detailed description
A comparative study for ridge augmentation procedure, With two groups. First group underwent a surgical ridge splitting procedure with ultrasonic bone surgery and grafting with Xenograft alone and implant placement. Second group underwent a surgical ridge splitting procedure with ultrasonic bone surgery Xenograft mix ed with Arginylglycylaspartic acid (RGD) and implant placement.
Both groups were followed up for 1 and 3 months after loading.
Interventions
- Drug RGD
Study group main material - Drug Xenograft
Scaffold material of choice - Procedure Split crest technique
Piezoelectric surgery
Primary outcome measures
- ISQ measurement for implant stability [Time frame: At time of surgery, at loading and 3 months after loading.]
Secondary outcome measures (1)
- Bone density around dental implants. [Time frame: At time of loading and 3 months after loading]
Eligibility criteria
Inclusion criteria
- Adults (age 18-30) exhibiting initial insufficiently bone width.
- Patients with good oral hygiene.
- Patients must be free from systemic diseases that may influence the outcome of the therapy.
- Patients with bony horizontal defects alone, Class III \& IV.
Exclusion criteria
- Heavy smokers.
- Patient treated by immunosuppressive chemotherapy or radio therapy,
- Allergy to any material or medication used in the study.
- Pregnant females.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Al Azhar University of Cairo — Cairo
Identifiers
NCT: NCT06585852 · RGD in Ridge splitting