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Enrolling by invitation NCT06582147

The Social Determinants of Health Screening and Referral Project

No phase Interventional Preterm Birth

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Implementation of social determinants of health screening and referral.
Who it may be relevant to
Registry conditions: Preterm Birth. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Implementing a Social Determinants of Health Screening and Referral Care Model in the Neonatal Intensive Care Unit

Overview

Up to a quarter of the families with preterm infants have unmet social needs, such as housing or job insecurity, which represent adverse social determinants of health (SDOH). Preterm infants are especially vulnerable to the social conditions they grow up in, with sustained impacts on function across multiple organ systems. The goal of this study is to translate an established model of SDOH screening and referral from the outpatient setting to the NICU, thereby maximizing the potential to offset the effects of adverse SDOH on vulnerable mother-preterm infant dyads.

Detailed description

The goal of this study is to implement SDOH screening and referral models in 7 safety net NICUs, examining their potential to offset the effects of adverse SDOH for a highly vulnerable population at the earliest stages of life. The investigators propose a hybrid effectiveness-implementation stepped wedge cluster randomized trial using the Proctor Conceptual Model of Implementation Research. The investigators will follow a cohort of 882 mother-infant dyads longitudinally for 12 months after NICU discharge to examine family, maternal, and infant outcomes. Each site will participate in three phases: usual, experimental, and sustainment.

The study aims are to:

Aim 1: Examine the implementation of SDOH screening and referral models into the NICU (acceptability, feasibility, penetration, equity, and sustainability).

Aim 2: Examine the effectiveness and equity of SDOH screening and referral models in the NICU setting on parental receipt of community resources for unmet social needs 3 months post-NICU discharge.

Aim 3: Explore the effectiveness of SDOH screening and referral models in the NICU to improve (a) maternal mental health (depression) and (b) health and developmental outcomes of preterm infants (quality of life, growth, development, and respiratory disease) during the 12 months post-NICU discharge.

Interventions

  • Other Implementation of social determinants of health screening and referral
    WE CARE is a relatively simple, low-intensity intervention that has two key components: (1) screening individuals using the WE CARE SDOH Screener for unmet social needs, and (2) providing individuals who have unmet social needs with SDOH Community Resource sheets

Primary outcome measures

  • Penetration of SDOH intervention [Time frame: Monthly for approximately 12 months]
  • Receipt of ANY Community Resource [Time frame: 3 months Post-NICU discharge]
Secondary outcome measures (12)
  • Acceptability of SDOH intervention [Time frame: Approximately 7, 9, and 12 months]
  • Feasibility of SDOH intervention [Time frame: Approximately 7, 9, and 12 months.]
  • Sustainability of SDOH intervention [Time frame: Monthly for approximately 6 months.]
  • Equity of implementation [Time frame: Monthly for approximately 18 months (during both penetration and sustainability).]
  • Equity of receipt of community resources [Time frame: 3 months Post-NICU discharge]
  • SDOH Risk [Time frame: Baseline, 3 months, 6 months, and 12 months Post-NICU discharge]
  • SDOH Desire Assistance [Time frame: Baseline, 3 months, 6 months, and 12 months Post-NICU discharge]
  • SDOH Community Resource [Time frame: Baseline, 3 months, 6 months, and 12 months Post-NICU discharge]
  • Family Economic Pressure [Time frame: Baseline, 3 months, 6 months, and 12 months Post-NICU discharge]
  • Maternal Wellbeing [Time frame: Baseline, 3 months, 6 months, and 12 months Post-NICU discharge]
  • Postpartum maternal primary care utilization [Time frame: 3 months, 6 months, and 12 months Post-NICU discharge]
  • Maternal Postpartum Obstetric Care Utilization [Time frame: 3 months, 6 months, and 12 months Post-NICU discharge]

Eligibility criteria

Inclusion criteria

  • Infant gestational age <34 weeks' gestation; singleton or multiple.
  • Infant hospitalized for at least 14 days of life (to allow for SDOH screening/referral and contact with resources if applicable).
  • Mother and infant are alive.
  • Mother speaks and reads English or Spanish.
  • Infant will be discharged home from the NICU (to allow for follow-up).
  • Mother will care for her infant(s) at home in the US for at least 12 months after discharge from the NICU.

Exclusion criteria

  • Mothers or infants who die before anticipated infant discharge.
  • Infant discharged after 52 weeks postmenstrual age.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Single group
Masking
Open label
Primary purpose
Health services research

Study locations

United States · 7 centers
  • Denver Health Hospital Authority — Denver
  • Shands Jacksonville Medical Center, Inc. DBA UF Health Jacksonville — Jacksonville
  • Children's Hospital of Michigan — Detroit
  • University of Mississippi Medical Center — Jackson
  • Children's Hospital at Montefiore — The Bronx
  • Cincinnati Children's Hospital Medical Center — Cincinnati
  • Temple University Hospital — Philadelphia

Identifiers

NCT: NCT06582147 · STUDY00000543 · 5R01HD104772

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗