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Recruiting NCT06578000

Efficacy of Iontophoresis in Treating Lateral Epicondylitis Patients

Phase I Interventional Lateral Epicondylitis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Magnesium sulfate, conventional therapy.
Who it may be relevant to
Registry conditions: Lateral Epicondylitis. Basic parameters: 20 years — 50 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Efficacy of Iontophoresis in Treating Lateral Epicondylitis Patients a Randomised Controlled Trial

Overview

This study is conducted To evaluate the effect of magnesium sulfate on pain intensity, muscle power, hand grip and function ability in patients with lateral epicondylitis.

Detailed description

This study is conducted To evaluate the effect of magnesium sulfate on pain intensity, muscle power, hand grip and function ability in patients with lateral epicondylitis.

BACKGROUND:

Lateral epicondylitis (LE) (tennis elbow) is a tendinopathy of the forearm extensor muscles, often caused by overuse or repetitive use (mostly of the extensor carpi radialis brevis), forced extension or direct trauma in the epicondyle . LE has an approximate rate of 40% and a prevalence of 1-3% of the general population . It mostly affects people 40 years and older. Some studies indicate that men and women are equally affected; others report a higher percentage of affected women .

HYPOTHESES

It will be hypothesized that:

There will be no statistically significant effect of magnesium sulfate on pain intensity, muscle power, hand grip and function ability in patients with lateral epicondylitis.

Definition of terms Lateral epicondylitis: pain and tenderness over the lateral epicondyle of the humerus, and pain on resisted dorsiflexion of the wrist, middle finger, or both .

Iontophoresis: is a technique used to enhance transdermal penetration of substances through the application of electric current .

RESEARCH QUESTION:

This study will be conducted to answer the following question:

What is the effect of magnesium sulfate on pain intensity, muscle power, hand grip and function ability in patients with lateral epicondylitis?

Interventions

  • Drug Magnesium sulfate
    Iontophoresis therapy (MgO4 will be applied to the active positive electrode and the treatment will be repeated twice a week for four weeks) + conventional therapy (Splint + Stretch + strength).
  • Other conventional therapy
    conventional therapy (Splint + Stretch + strength) twice a week for six weeks

Primary outcome measures

  • to investigate the effect of magnesium sulfate on pain intensity [Time frame: 6 weeks]
  • investigate the effect of magnesium sulfate on muscle power in patients with lateral epicondylitis. [Time frame: 6 weeks]
  • investigate the effect of magnesium sulfate on hand grip in patients with lateral epicondylitis. [Time frame: 6 weeks]
  • investigate the effect of magnesium sulfate on function ability in patients with lateral epicondylitis. [Time frame: 6 weeks]
Secondary outcome measures (1)
  • Elbow range of motion [Time frame: 6 weeks]

Eligibility criteria

Inclusion criteria

  • • Their age will be ranged between 20-50 years with both gender
  • Pain on the lateral side of the elbow for at least 4 weeks
  • Tenderness over the lateral epicondyle
  • At least two positive provocative tests: Mill test and Thomson test

Exclusion criteria

  • • History of injection, surgery, physical therapy in the elbow area in the last 3 months
  • Previous elbow surgery
  • History of radius/ulna fracture
  • History of cervical and shoulder problems
  • Having bilateral symptoms
  • Concomitant medial epicondylitis
  • Malignancy
  • Pregnancy
  • Systemic rheumatologic disease or systemic infection
  • Inserted cardiac pacemaker
  • Presence of coagulation disorders
  • Cognitive dysfunction

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Faculty of Physical Therapy — Cairo

Identifiers

NCT: NCT06578000 · P.T.REC/012/004798

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗