Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy; A Randomized Controlled Clinical Trial
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Laparoscopic myomectomy with intramyometrial injection of diluted epinephrine, traditional laparoscopic myomectomy, laparoscopic myomectomy with temporary bilateral uterine artery occlusion, injection of epinephrine 1mg diluted in 200mg of NaCl.
- Who it may be relevant to
- Registry conditions: Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy. Basic parameters: 18 years — 39 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine will be important to reduce intraoperative bleeding, time of operation and hospitalization period after laparoscopic myomectomy.
Detailed description
Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine will be important to reduce intraoperative bleeding, time of operation, and hospitalization period after laparoscopic myomectomy.
This will be the first study to investigate the efficacy of Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine in minimizing blood loss during Laparoscopic myomectomy at our university.
Can Laparoscopic myomectomy with temporary bilateral uterine artery occlusion or intramyometrial injection of diluted epinephrine give better outcomes regarding intraoperative bleeding when compared to traditional laparoscopic myomectomy?
Interventions
- Procedure Laparoscopic myomectomy with intramyometrial injection of diluted epinephrine
intramyometrial injection of epinephrine 1mg diluted in 200mg of NaCl solution - Procedure traditional laparoscopic myomectomy
traditional laparoscopic myomectomy - Procedure laparoscopic myomectomy with temporary bilateral uterine artery occlusion
Experimental: laparoscopic myomectomy with temporary bilateral uterine artery occlusion - Drug injection of epinephrine 1mg diluted in 200mg of NaCl
injection of epinephrine 1mg diluted in 200mg of NaCl
Primary outcome measures
- blood loss [Time frame: intra-operative]
Eligibility criteria
Inclusion criteria
- Women aged from 18 to 39 years.
- Symptomatizing Women (heavy menstrual bleeding or subfertility).
- FIGO stage (3-7) by ultrasound.
- Only uterine corpus fibroid.
- Up to three fibroids by ultrasound.
- No previous hormonal treatment.
Exclusion criteria
- Patients with bleeding tendency.
- Patients who refuse to participate in the study or uncooperative patients.
- Current pregnancy.
- Any retroperitoneal surgery at pararectal space.
- More than one cesarean delivery.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Prevention
Study locations
Egypt · 1 center
- Zagazig University — Zagazig
Identifiers
NCT: NCT06566352 · 218/12-3-2024