Development, Standardisation and Standardisation Project for a New Memory Assessment
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: New memory assessment.
- Who it may be relevant to
- Registry conditions: Memory Disorders. Basic parameters: from 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Episodic memory (EM) is a neuropsychological marker of Alzheimer's disease (AD) (Thomas-Anterion, 2006). Current tests for its assessment do not take into account the identity and emotional aspects of memory (Van der Linden et al., 2018). However, there are models that integrate links with identity, self-awareness and experience. Pause et al. (2013) propose criteria to create ecological tools, including consideration of the emotional valence of memories and the spatio-temporal context of acquisition. In line with these criteria, we have developed a new tool: the NEM (New evaluation of Episodic Memory). Preliminary studies show different response profiles on the NEM among patients (Launay et al., 2023). We now want to evaluate the relevance of this tool in the differential diagnosis of AD.
Interventions
- Other New memory assessment
The intervention is part of the neuropsychological assessment carried out as part of routine care. It consists of carrying out the neuropsychological tests traditionally used to investigate the diagnostic hypothesis of Alzheimer's disease.
Primary outcome measures
- Score total NEM (new memory assessment) [Time frame: baseline]
Secondary outcome measures (3)
- NEM sub-scores [Time frame: baseline]
- Total RL/RI 16 Recall [Time frame: baseline]
- Delayed Mem Logic Recall [Time frame: baseline]
Eligibility criteria
Inclusion criteria
- Age ≥ 50 years
- Ability to understand judged sufficient by the assessor;
- Amnesic MCI profile (Petersen, 2003) during the 1st medical consultation prior to the assessment being prescribed.
Exclusion criteria
- Severe auditory and/or visual sensory impairment not compatible with neuropsychological assessment;
- Judged fit to take the test by the assessor;
- Patient under guardianship, curatorship or family guardianship;
- Opposition to data processing.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
France · 1 center
- University hospital — Tours
Identifiers
NCT: NCT06564779 · DR240067-NEM