Not yet recruiting NCT06559358
Subthreshold Stimulation Versus Suprathreshold Stimulation in People With Chronic Low Neck Pain
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: electrical stimulation.
- Who it may be relevant to
- Registry conditions: Pain, Trigger Point Pain, Myofascial. Basic parameters: 40 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
this trial will involve three groups. Group 1 will receive subthreshold stimulation. Group 2 will receive suprathreshold stimulation. Group 3 will receive shame treatment.
Interventions
- Device electrical stimulation
A two-channel portable electrical stimulation unit (BTL-4620, Czech Republic).
Primary outcome measures
- Pain intensity [Time frame: 2-3 months]
- Pressure threshold [Time frame: 2-3 months]
- Electromyography [Time frame: 2-3 months]
- Range of motion [Time frame: 2-3 months]
Eligibility criteria
Inclusion criteria
- Age from 40 to 65 years old participated in this study, 2
- Having neck pain for more than 6 months with a grade five or greater on the visual analog scale
- Having one or more trigger points in the upper trapezius muscle,
- A significant increase in neck muscle EMG activity indicates the presence of tender points.
Exclusion criteria
- Taking non-pharmacological therapies (e.g., acupuncture, physical therapy, osteopathy)
- Taking oral or intravenous pain therapy, intramuscular or subcutaneous injection of cortisone, or local anesthetics during the study period,
- Presence of any contraindication to electrical current including pregnancy, epilepsy, cardiac arrhythmia, cardiac surgery, implanted pacemaker or defibrillator, previous surgery in the spinal cord, infectious diseases of the spinal cord, malignant tumors with or without secondary blastomas in the spinal cord, severe radicular pain with acute paralysis in the extremities
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Quadruple blind
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Mohamed AA, Hamed RH, Mohamed DA, Hussien OA. Effect of Nociceptors Hypostimulation Versus Nociceptors Hyperstimulation on Electromyography of Cervical Muscles, Myofascial Trigger Points Sensitivity, Pain, and Disability in Patients With Chronic Cervical Pain: A Randomized Double-Blinded Controlled Trial. Physiother Res Int. 2026 Apr;31(2):e70192. doi: 10.1002/pri.70192. PMID 41831217
Identifiers
NCT: NCT06559358 · Beni-Suef University2