Immersive Virtual Reality Exergames and Office Workers' Cardiometabolic Health
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: 12-week at-home immersive virtual reality exergame.
- Who it may be relevant to
- Registry conditions: Exergaming, Metabolic Syndrome. Basic parameters: 18 years — 64 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
At-home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial
Overview
The worldwide increasing of prevalence of non-communicable diseases has grown the recognition of necessity for identifying the modifiable risk in preventing and managing these diseases. While, the office worker, as a representative group of physical inactivity, is exposed to risk factor of metabolic syndrome which is considered as the pathway of non-communicable diseases. This study mainly focuses on the purpose of examining the interventional efficacy of at-home immersive virtual reality exergame on several metabolic syndrome biomarkers among office workers. In addition, it purposes to determine the impacts of at-home immersive virtual reality exergame on lifestyle pattern of office workers. A 2-armed, single blinded randomized controlled trial (RCT) will be applied to examine the therapeutic effects of at-home immersive virtual reality exergame in this exploratory study. 120 Japanese office workers with less than 150 minutes per week of moderate to vigorous sports activities will be recruited by a convenience sample method. They are randomly allocated to two parallel groups, which including an intervention group: 12-week training of at least 150 minutes per week at-home immersive virtual reality exergame playing with a set device of Meta Quest 2, a control group: 12-week of maintaining regular exercise, eating, and working habits without making significant changes. During this 12-week trial, 3 main follow up steps are included at the timelines of 0 week, 6 weeks, 12 weeks. For each follow up, we will collect three types of variables, including major clinical risk factors of metabolic syndrome, lifestyle pattern factors of metabolic syndrome, and demographics (0 week only). To analysis the variance between intervention group and control group, mixed linear model will be applied to understand the efficacy result of this intervention. The variances of metabolic syndrome clinical risk factors between groups would be used to express the therapeutic effects of at-home immersive virtual reality exergame. The changes of lifestyle pattern factors would be applied to show the impacts of at-home immersive virtual reality exergame on lifestyle pattern.
Interventions
- Behavioral 12-week at-home immersive virtual reality exergame
12-week training of at least 150 minutes per week at-home immersive virtual reality exergame playing with a set device of Meta Quest 2 and maintaining regular eating and working habits without making significant changes.
Primary outcome measures
- High-density lipoprotein cholesterol (HDL-C) [Time frame: Baseline (0 week), Mid-follow up (6-week), Final follow up (12-week).]
- Low-density lipoprotein cholesterol (LDL-C) [Time frame: Baseline (0 week), Mid-follow up (6-week), Final follow up (12-week).]
- Impaired fasting glucose [Time frame: Baseline (0 week), Mid-follow up (6-week), Final follow up (12-week).]
- Triglycerides [Time frame: Baseline (0 week), Mid-follow up (6-week), Final follow up (12-week).]
- Hypertension [Time frame: Baseline (0 week), Mid-follow up (6-week), Final follow up (12-week).]
- Body mass index [Time frame: Baseline (0 week), Mid-follow up (6-week), Final follow up (12-week).]
Secondary outcome measures (2)
- Exercise time (including exergaming time) [Time frame: Baseline (0 week, self estimation), Mid-follow up (1-6 week), Final follow up (7-12 week).]
- Sedentary time [Time frame: Baseline (0 week, self estimation), Mid-follow up (1-6 week), Final follow up (7-12 week).]
Eligibility criteria
Inclusion criteria
- 18-64 years old
- Capable of standing and exercising.
- Having no history of diagnosis of heart disease, cancer, or dementia.
- Being interested in playing with the exergames.
- Willingness of adhering to a 12-week interventional exergame treatment.
Exclusion criteria
- Individuals who are already engaged in more than 150 minutes per week of moderate to vigorous activities.
- Individuals with some pharmacological treatments, some surgery (bariatric surgery), and some traditional Chinese medicine.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Prevention
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Zhao J, Yasunaga A, Kaczynski AT, Park H, Luo Y, Li J, Shibata A, Ishii K, Yano S, Oka K, Koohsari MJ. At-Home Immersive Virtual Reality Exergames to Reduce Cardiometabolic Risk Among Office Workers: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2025 Jan 20;14:e64560. doi: 10.2196/64560. PMID 39832174
Identifiers
NCT: NCT06556784 · VRGOWH2024Z