Post Surgical Multimodal Analgesia With Oral Strong Opioids
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Multimodal analgesia with oral strong opioids.
- Who it may be relevant to
- Registry conditions: Orthopedic Procedures, Arthroplasty, Fracture Fixation. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Taiwan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Study on the Clinical Effectiveness of Oral Strong Opioids for Common Orthopedic Surgeries Following Multimodal Analgesia
Overview
This is a prospective observational case study, focusing on the clinical effectiveness of oral strong opioids for pain management following common orthopedic surgeries.The study aims to evaluate the effectiveness of multimodal analgesia with oral strong opioids, reduce common opioid-related side effects, and improve patient compliance and satisfaction.
Interventions
- Drug Multimodal analgesia with oral strong opioids
Physician's choice of post-surgical multimodal analgesia with an oral strong opioid as the backbone analgesics
Primary outcome measures
- Change in pain scores from baseline [Time frame: Twice daily during hospitalization (approximately within 1 week), at the first return 1 day visit and at 3 months after surgery]
Secondary outcome measures (4)
- Occurence of adverse events [Time frame: During hospitalization (approximately within 1 week)]
- Compliance of oral strong opioids [Time frame: During hospitalization (approximately within 1 week)]
- Physician's global impression - improvement scale(CGI-I) [Time frame: During hospitalization (approximately within 1 week), at the first return 1 day visit and at 3 months after surgery]
- Satisfation of the pain control as per patients' report outcome [Time frame: End of hospitalization (approximately 1 week after surgery)]
Eligibility criteria
Inclusion criteria
- Aged 18 or older
- Must undergo one of the following treatments:
(1) Fracture of upper or lower limbs or pelvis requiring internal fixation surgery (2) Spinal fusion surgery (3) Joint replacement surgery 3. Requiring multimodal analgesics for postoperative pain control, with oral strong opioids as the primary opioid analgesic, as assessed by his/her physician.
4\. Voluntarily sign the informed consent form and agree to the collection of clinical questionnaires and medical-related information for this study.
Exclusion criteria
- Patients who have not received any or have only received oral potent opioids for no more than 1 day during the postoperative hospitalization period (including those known to be intolerant or allergic to opioid medications).
- Patients who have received or are expected to use long-acting opioid injections within 7 days before surgery or during the postoperative hospitalization period.
- Patients who use patient-controlled analgesics for pain control after surgery.
- Patients with a history of substance abuse or who require continuous treatment with other opioid receptor agonists or antagonists (such as naloxone or methadone).
- Patients with a history of mental illness who continue to require medication control from 28 days before surgery and until discharge.
- Other cases deemed ineligible by the study investigator.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Taiwan · 1 center
- TriService General Hospital — Taipei
Identifiers
NCT: NCT06554457 · ORORA24