Consistency of LGE-MRI Fibrosis and EAM Low-voltage Area
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: LGE-MRI Scan.
- Who it may be relevant to
- Registry conditions: Atrial Fibrillation. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Exploratory Study of Consistency of Bi-Atrial Fibrosis Detected by Late Gadolinium Enhancement Magnetic Resonance Imaging and Low Voltage Area of Electroanatomic Mapping
Overview
This study aims to: 1. Assess the consistency of LGE-MRI bi-atrial fibrosis and electroanatomical mapping of bi-atrial low voltage region 2. To evaluate the electroanatomical characteristics of different types of fibrosis (dense fibrosis, patchy fibrosis, etc.) in different locations of the left and right atrium; 3. To explore the correlation between preoperative and postoperative bi-atrial fibrosis and long-term recurrence in patients with atrial fibrillation.
Interventions
- Diagnostic test LGE-MRI Scan
Participants will receive LGE-MRI scan before catheter ablation and 3 months after catheter ablation
Primary outcome measures
- Consistency of LGE-MRI fibrosis and EAM low-voltage area [Time frame: Baseline (at recruit time point)]
Eligibility criteria
Inclusion criteria
- Adult patients (≥18 years old) who are willing to participate in this study and can sign informed consent;
- Atrial fibrillation was diagnosed and catheter ablation was proposed
Exclusion criteria
- Left atrial thrombus or left atrial appendage thrombus;
- Severe chronic obstructive pulmonary disease (FEV1/ FVC<70%, FEV1<50% predicted value);
- Absolute contraindications of anticoagulation therapy;
- Currently pregnant;
- Contraindications for LGE-MRI (claustrophobia, pacemaker implantation, eGFR<30ml/min for renal insufficiency, severe obesity, pregnancy, gadolinium chelating agent allergy, etc.);
- refuse to participate in the study;
- other physical or mental incapacity to participate in the study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Fuwai Hospital, CAMS&PUMC — Beijing
Identifiers
NCT: NCT06552845 · 2023-2223