Construction of a Cohort for Pan-Vascular Disease Among Employees of Taizhou People's Hospital
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cardiovascular Death, Myocardial Infarction, Stroke. Basic parameters: from 45 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
1. Participant Recruitment During the annual health check-ups for hospital staff, potential participants are recruited. Those who express interest are provided with a detailed explanation of the study's objectives, content, and procedures, and are required to sign an informed consent form. 2. Screening Phase Medical history is collected, including any previous occurrences of myocardial infarction, ischemic or hemorrhagic stroke, or history of coronary, carotid, or peripheral arterial revascularization. 3. Baseline Data Collection 1\. Health Questionnaire Survey: Collect demographic information, medical history, and data on nutrition, physical activity, and smoking habits through a questionnaire. 2\. Clinical Assessments: Conduct the following assessments for all enrolled participants: * High-sensitivity cardiac troponin I and NT-proBNP testing * Non-invasive arterial stiffness testing * Measurement of visceral and subcutaneous fat content * Fundus photography * Body composition analysis 4 Regular Follow-Up Annual follow-up for a total of 10 years. The follow-up includes: 1. . Collection of updated demographic information and medical history, as well as repeated questionnaires on nutrition, physical activity, and smoking habits. 2. . Reassessment of the following items: * High-sensitivity cardiac troponin I and NT-proBNP testing * Non-invasive arterial stiffness testing * Measurement of visceral and subcutaneous fat content * Fundus photography * Body composition analysis 5 Outcome Evaluation 1）. Primary Outcomes: Cardiovascular mortality, non-fatal myocardial infarction, or non-fatal stroke events. 2）. Secondary Outcomes: All vascular events, changes in cardiovascular biomarkers, and degree of arterial stiffness.
Primary outcome measures
- Cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke events [Time frame: September 2024 to August 2034]
Eligibility criteria
Inclusion criteria
- Employed or retired individuals aged 45 years or older;
- Willing to sign an informed consent form and voluntarily participate in health examinations and related data collection.
Exclusion criteria
- History of myocardial infarction, ischemic or hemorrhagic stroke, or revascularization of coronary, carotid, or peripheral arteries;
- Employees with severe psychological disorders who are unable to cooperate with the study;
- Pregnant or breastfeeding women.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06545799 · KY 2024-098-01