Impact of Belt Position on the Results of PEEP Titration by EIT During ARDS
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: EIT.
- Who it may be relevant to
- Registry conditions: ARDS. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Impact of Belt Position on the Results of PEEP Titration by Electrical Impedance Tomography During Acute Respiratory Distress Syndrome
Overview
ARDS is a frequent reason for hospitalization in intensive care. In order to improve its management, doctors seek to limit the mechanical ventilation-induced injuries (VILI) that can occur. PEEP is a parameter that plays a role in the appearance of VILI, and its adjustment can be optimized by EIT. The EIT is a non-invasive, non-irradiating, real-time monitoring device, today widely used for the optimization of ventilation in patients intubated for ARDS. The positioning of the EIT belt at different chest heights could influence the result of the PEEP titration.
Detailed description
The aim of this study is to test the hypothesis that the position (2nd intercostal space or 5th intercostal space) of the EIT (Electrical Impedance Tomography) belt significantly influences the result of PEEP (Positive Expiratory Pressure) titration.
Interventions
- Device EIT
Two PEEP titrations monitored by EIT will be performed, each with the electrode belt positioned at a different chest height (2nd intercostal space or 5th intercostal space). The order will be drawn at random.
Primary outcome measures
- Impact of the position of the electrode belt on the results of PEEP titration by EIT. [Time frame: Day 0]
Secondary outcome measures (3)
- Impact of the existence of intra-tidal recruitment on the discordance between PEPEIT and PEPCRS [Time frame: Day 0]
- Factors associated with a discordance between PEPEIT and PEPCRS [Time frame: Day 0]
- Discrepancy between compliance measured according to impedance and compliance measured according to exhaled volume [Time frame: Day 0]
Eligibility criteria
Inclusion criteria
- Occurrence of moderate to severe ARDS (PaO2/FiO2 ratio ≤ 200 mmHg) within 72 hours following intubation
- Criteria for moderate to severe ARDS for less than 72 hours
- Passive ventilation in controlled assisted ventilation (no spontaneous ventilation)
- Consent of next of kin
Exclusion criteria
- Age < 18 years
- ECMO
- Pneumothorax
- Pacemaker or implantable defibrillator
- Chest trauma in the last 3 months
- Skin peeling (Burned, Lyell)
- Intracranial hypertension
- Uncontrolled shock (noradrenaline >5 mg/h)
- Pregnant woman
- Adult patient protected within the meaning of the law
- Lack of social security
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Other
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06541522 · REPEIT