Efficacy of Remifentanil in Preventing Emergence Agitation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Remifentanil, N2O, Fentanyl.
- Who it may be relevant to
- Registry conditions: Emergence Agitation. Basic parameters: 18 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Efficacy of Remifentanil in Preventing Emergence Agitation in Patients Undergoing Nasal Surgery Under Desflurane Anesthesia: A Prospective Double-blind Randomized Controlled Trial.
Overview
The primary aim of the study was to test the hypothesis that remifentanil administered for analgesia prevents emergence agitation more effectively than fentanyl and N2O in patients undergoing rhinoplasty who received desflurane as an inhaled anesthetic agent. The secondary aim of the study was to compare the demographic data, intraoperative and postoperative hemodynamic data, surgical time and modified Aldrete score of patients who received different intraoperative analgesia methods.
Interventions
- Drug Remifentanil
remifentanil infusion - Drug N2O
Use of N2O for analgesia - Drug Fentanyl
Use of Fentanylfor analgesia
Primary outcome measures
- Richmond Agitation-Sedation Scale (RASS) [Time frame: Postoperative care unit 1.second_5. second_15.second]
Secondary outcome measures (2)
- mean arterial pressure [Time frame: Before induction ,After intubation 1 min,After intubation 5 min, After intubation 15 min After intubation 30 min]
- Heart rate [Time frame: Before induction ,After intubation 1 min,After intubation 5 min, After intubation 15 min After intubation 30 min]
Eligibility criteria
Inclusion criteria
The study included patients over the age of 18, planned to undergo rhinoplasty by the plastic and reconstructive surgery department, and American Society of Anesthesiologist (ASA) I-II.
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Exclusion criteria
- Patients with a known history of allergy to the drugs to be administered in the study, ASA III and above, body mass index (BMI) 35>kg/m2, younger than 18 years of age, any problems that would prevent general anesthesia in the preoperative evaluation (upper respiratory tract infection, etc.), and those who did not agree to participate in the study were excluded from the study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Treatment
Study locations
Turkey (Türkiye) · 1 center
- Health Sciences University Gazi Yaşargil Training and Research Hospital — Diyarbakır
Identifiers
NCT: NCT06539013 · HTosunSONE