B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Immunohistochemical staining.
- Who it may be relevant to
- Registry conditions: Cutaneous Squamous Cell Carcinoma. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Expression of B-catenin in Cutaneous Squamous Cell Carcinoma and Its Mimickers
Overview
Examine the role of B-catenin in differentiation of cutaneous squamous cell carcinoma from other lesions that may be similar to it
Detailed description
Skin cancer is one of the most common form of cancer worldwide. Cutaneous squamous cell carcinoma is one of most common skin tumers that caused by many factors as ultra violet ,ionizing radiation and others . It was an advanced spectrum ranging from actinic keratosis to invasive and metastatic squmous cell carcinoma. Correct identification of cutaneous squamous cell carcinoma is a challenge as it has both clinically and histopathologically mimickers.
So the aim of this study is to identify the expression of B-catenin in cutaneous Squamous cell carcinoma and its mimickers.
Interventions
- Biological Immunohistochemical staining
Staining of cutanous squamous cell carcinoma and its mimickers by monoclonal antibodies against human B-catenin by immunohistochemical procedures
Primary outcome measures
- Detection of B-catenin expression in cutanous squamous cell carcinoma and its mimickers [Time frame: 6 month]
Eligibility criteria
Inclusion criteria
- tissue blocks with sufficient materials Cases with sufficient data
Exclusion criteria
- tissue blocks with insufficient and necrotic materials. Casas with insufficient data
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Egypt · 1 center
- Sohag University hospital — Sohag
Identifiers
NCT: NCT06536946 · Soh-Med-25-05-07MS