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Recruiting NCT06524843

Fracture Risk Evaluation of Bone Metastases Derived From Carcinoma

Observational Bone Metastases

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Analysis.
Who it may be relevant to
Registry conditions: Bone Metastases. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Generation of Synthetic Patient Data (RAW) for Risk Evaluation of Bone Metastases Derived From Carcinoma

Overview

From the archives of the Rizzoli institute all patients (approximately 750) treated for bone metastases from 01/01/2010 to 31/12/2022. A review will be made from the medical records, radiological imaging, and histological data of these patients

Interventions

  • Other Analysis
    Analysis and review of imaging and clinical data

Primary outcome measures

  • Creation a dataset of clinical data and diagnostic images [Time frame: At baseline (Day 0)]

Eligibility criteria

Inclusion criteria

  • Age ≥ 18 years
  • Diagnosis of bone metastasis from carcinoma, regardless of the type of carcinoma, and of the number and location of the metastases
  • Availability of imaging and clinical data
  • Availability of at least one follow-up during the last 12 months form diagnosis

Exclusion criteria

  • At least one inclusion creteria not met

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Italy · 1 center
  • IRCCS Istituto Ortopedico Rizzoli — Bologna

Publications

  • Mirels H. Metastatic disease in long bones: A proposed scoring system for diagnosing impending pathologic fractures. 1989. Clin Orthop Relat Res. 2003 Oct;(415 Suppl):S4-13. doi: 10.1097/01.blo.0000093045.56370.dd. PMID 14600587
  • Coleman RE. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res. 2006 Oct 15;12(20 Pt 2):6243s-6249s. doi: 10.1158/1078-0432.CCR-06-0931. PMID 17062708

Identifiers

NCT: NCT06524843 · FRAIL-RAW

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗