Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Periodontitis -A RCT
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Bromelain gel, chlorhexidine gel, SRP.
- Who it may be relevant to
- Registry conditions: Periodontal Pocket. Basic parameters: 30 years — 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- India
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis -Randomized Control Clinical Trail
Overview
The current study is a prospective randomised study Evaluation of 2%Bromelain Gel With 0.2%Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing in Stage II/III and Grade B Periodontitis
Detailed description
36 sites with periodontal pocket depth measuring 4-6mm were selected. The sites selected were divided into
1. Group I (Control)- 12 sites with Probing depth of ≥5mm treated with scaling and root planing alone. 2. Group II -12 sites with Probing depth of ≥5mm treated with scaling and root planing followed by placement of bromelain gel. 3. Group III -12 sites with Probing depth of ≥5mm treated with scaling and root planing followed by placement of chlorhexidine gel.
periodontal pack was placed and patient was recalled at 1week,4th week and 12th week
Interventions
- Drug Bromelain gel
bromelain gel is prepared from bromelain capsules in laboratory - Drug chlorhexidine gel
chlorhexidine gel is prepared from mouth wash - Procedure SRP
Scaling and root planing was done with ultra sonic and hand scaling
Primary outcome measures
- Probing pocket Depth (PPD) [Time frame: 3 months]
- Relative attachment level (RAL) [Time frame: 3 months]
Secondary outcome measures (3)
- Plaque Index [Time frame: 3 months]
- Gingival index [Time frame: 3 month]
- Modified Sulcus Bleeding Index [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
- Patient with have chronic periodontitis in the age group between 30-50 years.
- Patients having ≥20 teeth.
-.Patients with radiographic evidence of bone loss in atleast two teeth.
- Patients who are systematically healthy.
- Patients with localized pockets with probing depth of ≤ 5mm.
- Patients who are cooperative and able to attend the hospital for regular follow-up.
Exclusion criteria
- Patients who have received any surgical or nonsurgical therapy during past 6months
- Pregnant or lactating females.
- Use of systemic antibiotics in the past 6 months.
- Patient who are not willing to give a written informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
India · 1 center
- Dr. NALLAGATLA VAMSI VENKATA KRISHNA SAI — Bengaluru
Identifiers
NCT: NCT06505759 · 02-D012-147453