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Recruiting NCT06497283

Binaural Sound for Remimazolam Maintenance

No phase Interventional General Anesthesia Prostate Cancer Stage Uterine Myoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Binaural sound.
Who it may be relevant to
Registry conditions: General Anesthesia, Prostate Cancer Stage, Uterine Myoma. Basic parameters: from 20 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
South Korea
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Effect of Intraoperative Binaural Sound on Remifentanil Dose Required for General Anesthesia Using Remimazolam: a Randomized, Placebo-controlled Trial

Overview

It is important to decrease the remifentanil dose for general anesthesia maintenance when using remimazolam. We will evaluate the effect of binaural sound on general anesthesia maintenance with remimazolam infusion.

Interventions

  • Procedure Binaural sound
    Binaural sound: Binaural sound will be applied.

Primary outcome measures

  • Intraoperative remifentanil dose [Time frame: At anesthesia day 0]
Secondary outcome measures (3)
  • Intraoperative remimazolam dose [Time frame: At anesthesia day 0]
  • Pain score (0:no pain, 10:maximal pain) [Time frame: At anesthesia day 0 and 1]
  • Electroencephalography [Time frame: At anesthesia day 0]

Eligibility criteria

Inclusion criteria

  • Patients scheduled for general anesthesia
  • Patients aged 20-60
  • Patients with American Society of Anesthesiologist physical status classification 1-2
  • Patients with ideal body weight 50-80 kg

Exclusion criteria

  • Patients with hearing disability
  • Patients using opioids or sedatives in 1 week
  • Patients who are dependent for alcoholics or drugs
  • Patients with hypersensitivities to remimazolam or remifentanil
  • Patients with arrhythmia, cardiovascular disease, heart failure, or hypovolemia
  • Patients with liver failure

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Supportive care

Study locations

South Korea · 1 center
  • Gangnam Severance Hospital — Seoul

Identifiers

NCT: NCT06497283 · 3-2024-0171

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗