IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Interpersonal psychotherapy.
- Who it may be relevant to
- Registry conditions: Depression, Interpersonal Relations. Basic parameters: 18 years — 24 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Brazil
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
IPT-based Group Intervention by Non-specialist for Improvement of Depressive Symptoms in Community Young Adults in Brazil: a Randomized Clinical Trial
Overview
Major depressive disorder is a highly prevalent, recurrent, and debilitating disease, the third cause of years of lost life in the world, and it may be the most common disease in 2030, according to the World Health Organization (WHO). Furthermore, it's also related to decreased quality of life and high mortality. Interpersonal psychotherapy (IPT) is a first-line treatment and can also be used for the prevention of depression. This randomized controlled clinical trial is planned to have 50 participants randomized between an interventional and a control group (waiting list). Our study covers young adults (18 to 24 years old) with depression. Participants will be invited by social media to undergo treatment in an IPT group. The intervention group will be separated into groups with up to 10 participants, with a weekly meeting for eight weeks. The intervention will focus on interpersonal relationships within the model of IPT and will be held by a university student and a doctor trained in IPT.
Interventions
- Behavioral Interpersonal psychotherapy
Interpersonal psychotherapy is a first-line treatment and can also be used for the prevention of depression.
Primary outcome measures
- Hospital Anxiety and Depression Scale (HADS) [Time frame: Pre-treatment, Week 1 to 8]
Secondary outcome measures (5)
- Patient Health Questionnaire-9 [Time frame: Pre-treatment, Week 1 to 8]
- Social support scale (MOS-SSS) [Time frame: Pre-treatment, Week 1 to 8]
- Quality of Life (WHOQOL-BREF) [Time frame: Pre-treatment, Week 1 to 8]
- Clinical Global Impression (CGI) [Time frame: Pre-treatment, Week 1 to 8]
- Beck Depression Inventory (BDI) [Time frame: Pre-treatment; Week 1-8]
Eligibility criteria
Inclusion criteria
- Young adults (between 18 and 24 years old)
- Young adults who work, live or study in Porto Alegre
- PHQ ≥ 5 - without suicide ideation
Exclusion criteria
- Maniac or hypomanic episode
- Psychotic Syndrome
- Substance Abuse
- Suicide Risk or Ideation
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Brazil · 1 center
- Clinical Hospital for Porto Alegre — Porto Alegre
Identifiers
NCT: NCT06480019 · 2023-0283