Appendicoliths in Acute Complicated Appendicitis Patients With Abscess
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Clinical data collection.
- Who it may be relevant to
- Registry conditions: Acute Complicated Appendicitis With Abscess. Basic parameters: 18 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Clinical Significance of Appendicoliths in Conservative Treatment of Acute Complicated Appendicitis Patients With Abscess: A Single-center Retrospective Study
Overview
Complicated appendicitis, characterized by the presence of an abscess or perforation, involves acute inflammation of the peritoneum secondary to an infection of the appendix, presenting additional challenges for management. Traditionally, the standard treatment for complicated appendicitis has been surgical intervention. However, conservative management, involving antibiotics and drainage, has emerged as a viable alternative for selected patients. Recent studies emphasize the importance of selecting appropriate antibiotics based on local resistance patterns and the patient's clinical condition. Broad-spectrum antibiotics, including those targeting anaerobic bacteria, are often preferred. In addition, advances in imaging technology, such as ultrasound-guided drainage, have improved the precision and success rates of percutaneous abscess drainage. This minimally invasive approach helps manage localized infections and can prevent the need for immediate surgery. One factor that has gained significant attention in determining the success of conservative treatment for acute complicated appendicitis is the presence of appendicoliths-calcified deposits within the appendix. This study aims to investigate the clinical significance of appendicoliths in the conservative management of acute complicated appendicitis with abscesses.
Interventions
- Other Clinical data collection
The clinical significance of appendicoliths in the conservative management of acute complicated appendicitis with abscesses.
Primary outcome measures
- The success rate of conservative treatment [Time frame: January 01, 2025 to December 31, 2025.]
Secondary outcome measures (3)
- Postoperative complications [Time frame: January 01, 2025 to December 31, 2025.]
- Length of postoperative hospital stay [Time frame: January 01, 2025 to December 31, 2025.]
- The surgical approach used [Time frame: January 01, 2025 to December 31, 2025.]
Eligibility criteria
Inclusion criteria
- Patients who aged ≥18 years, who diagnosed as acute appendicitis clinically, who had peri-appendiceal abscess larger than 2 cm in diameter on CT scan, who agreed conservative treatment first, who refused immediate emergency surgery
Exclusion criteria
- Patients younger than 18 years, those with malignancies, those with incomplete clinical or pathological records were excluded from the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06469086 · Zhongshan-HHY-05