Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Demineralized Dentin Allograft, Demineralized Dentin Autograft.
- Who it may be relevant to
- Registry conditions: Alveolar Bone Loss. Basic parameters: 25 years — 35 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Demineralized Dentin Allograft Versus Demineralized Dentin Autograft for Socket Preservation After Surgical Extraction of Impacted Mandibular Third Molar
Overview
This study is designed to evaluate and compare clinically and radiographically the effectiveness of Demineralized Dentin Allograft (DDA) versus Demineralized Dentin Autograft (Auto-DD) for preservation of alveolar ridge dimensions after surgical extraction of the impacted mandibular third molar.
Interventions
- Procedure Demineralized Dentin Allograft
20 sockets are randomly allocated to receive the Demineralized Dentin Allograft (split-mouth study) - Procedure Demineralized Dentin Autograft
20 sockets are randomly allocated to receive the Demineralized Dentin Autograft (split-mouth study)
Primary outcome measures
- Measuring and comparing the height of bone between the two groups [Time frame: Immediately post-operative, 3months post-operative, 6months post-operative]
- Measuring and comparing the width of bone between the two groups [Time frame: Immediately post-operative, 3months post-operative, 6months post-operative]
Secondary outcome measures (4)
- Assess and comparing the mouth opening of both groups [Time frame: One day post-operative, one week post-operative]
- Assess and comparing the swelling of both groups [Time frame: One day post-operative, one week post-operative]
- Assess and comparing the pain of both groups [Time frame: One day post-operative, one week post-operative]
- Assess and comparing the soft tissue parameters (bleeding on probing and color of the gingiva) of both groups [Time frame: One day post-operative, one week post-operative]
Eligibility criteria
Inclusion criteria
- Patients aged between 25 to 35 years old.
- Patients scored as (ASA I).
- No adverse habits such as smoking, tobacco chewing, alcohol.
- Patients having bilaterally impacted mandibular third molar with similar degree of difficulty according to (Kim JY, et al).
- The recipient alveolar sockets are free of any pre-existing periapical pathology, based on x-ray.
- Alveolar sockets with a depth of 5 mm or more, using periodontal probe for assessment.
- Patients sign a consent for all procedures.
Exclusion criteria
- 1\) Pregnant or lactating patients. 2) Relevant systemic diseases. 3) Patients with history of chemotherapy or radiotherapy.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Faculty of Dentistry- Horus University in Egypt — Damietta
Publications
- Joshi CP, D'Lima CB, Samat UC, Karde PA, Patil AG, Dani NH. Comparative Alveolar Ridge Preservation Using Allogenous Tooth Graft versus Free-dried Bone Allograft: A Randomized, Controlled, Prospective, Clinical Pilot Study. Contemp Clin Dent. 2017 Apr-Jun;8(2):211-217. doi: 10.4103/ccd.ccd_147_17. PMID 28839405
- Grover V, Kapoor A, Malhotra R, Sachdeva S. Bone allografts: a review of safety and efficacy. Indian J Dent Res. 2011 May-Jun;22(3):496. doi: 10.4103/0970-9290.87084. PMID 22048602
Identifiers
NCT: NCT06457373 · (DDA) for socket preservation