Prioritising Patient Medication Review: Hospitals Reaching Out
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Clinical pharmacist.
- Who it may be relevant to
- Registry conditions: Medication Review, Polypharmacy, General Practitioners, Interdisciplinary Communication. Basic parameters: from 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Denmark
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Prioritising Patient Medication Review: Hospitals Reaching Out (PriPMed)
Overview
To examine the effect of a cross-sectoral medication review intervention to admitted multi-morbid, polypharmacy patients aged 65+ at SHS in two settings; an acute admission unit (typical admission time \< 48 hours) and a medical outpatient setting (patients routinely visits for follow-up, diagnosis or treatment, but do require a bed or overnight care).
Detailed description
Lack of medication treatment coordination among especially multi-morbid patient's results in suboptimal medication treatment, adverse effects, increased use of resources, hospital admissions and premature death. Further, an aging population is a challenge to healthcare systems worldwide as older adults are vulnerable to non-communicable diseases and multi-morbidity. The age distribution varies across Denmark creating demographic inequality with a higher proportion of elderly in several municipalities in Southern Jutland and on a national level, the population aged 70+ already accounts for more than a third of all hospital days.
As the population ages, the concept of frailty becomes increasing in the provision of health care to an ageing population, and the Clinical Frailty Scale (CFS) can be used as a judgement-based frailty tool to evaluate specific domains including comorbidity, function, and cognition to generate a frailty score. In addition, an attempt to detect patients at high risk of medication errors is the Medicine Risk Score (MERIS) where acutely admitted patients are allocated into low and high risk of potential ADEs by predefined detection limits. Further, These components will be used to determine
In addition, an understudied patient group within polypharmacy and PIPs, are patients with dementia creating inequality among patient groups. The use of polypharmacy and Potential Inappropriate Prescribing are widespread in this patient group, and dementia is well-known to have a negative effect on overall mortality, which demonstrates the need for interventions to improve medication treatment in people with dementia. Intervention studies have examined the effects of pharmacist-led medication reviews in different hospital settings with various outcomes, but no exact model for prioritising patient medication review exists. Thus, there is a need to identify patients who will benefit most from a medication review in terms of outcomes, such as readmission, emergency department and general practitioner contacts. The aim of this project is to examine the effect of a cross-sectoral medication review between a clinical pharmacist and a medical specialist in coordination with the General Practitioner (GP), including patients from Hospital Sønderjylland, University Hospital of Southern Denmark (SHS).
Interventions
- Other Clinical pharmacist
The clinical pharmacist calls the patients' GP 90 days after discharge for follow-up
Primary outcome measures
- Readmission and emergency department rate. [Time frame: Up to thirty days after discharge]
Secondary outcome measures (5)
- Acute admission [Time frame: Up to 90 days after discharge]
- Mortality [Time frame: 30 and 90 days after discharge]
- GP contacts [Time frame: Up to 90 days after discharge]
- Implementation rate [Time frame: Up to 90 days after discharge]
- Compliance with medical treatment [Time frame: Up to 90 days after discharge]
Eligibility criteria
Inclusion criteria
- all hospitalized patients who are prescribed at least seven medications specified in the Electronic Patient Journal (EPJ) at admission
Exclusion criteria
- terminal patients or patients with a short life expectancy, patients residing in another region, patients who are discharged on the day of inclusion, and finally patients who do not speak Danish.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Health services research
Study locations
Denmark · 1 center
- Sygehus Sønderjylland — Aabenraa
Publications
- Schlunsen M, Revell JHP, Holtved E, Sondergaard J, Brandt F, Kjeldsen LJ. Challenges and solutions across sectors in multi-dose drug dispensing. Dan Med J. 2026 Mar 19;73(4):A03250182. doi: 10.61409/A03250182. PMID 41978445
Identifiers
NCT: NCT06451692 · SHS-Pharm2 - 2024