Prospective Evaluation of Disparities in Provision of Allogeneic Transplantation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Patient Ancestry Questionnaires.
- Who it may be relevant to
- Registry conditions: Allogeneic Transplantation. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).
Detailed description
Primary Objectives To prospectively evaluate graft options and choice of donor by patient ancestry and SES for allograft candidates at MDACC.
Secondary Objectives
* To prospectively evaluate time to transplant for allograft candidates at MDACC. * To evaluate treatment-related mortality for allograft candidates at MDACC. * To assess overall survival for allograft candidates at MDACC. * To prospectively evaluate receipt of preferred unrelated donor for allograft recipients at MDACC. * To evaluate receipt of an optimal graft for allograft recipients at MDACC.
Interventions
- Behavioral Patient Ancestry Questionnaires
Participants will be asked to complete a demographics and ancestry questionnaire at the baseline visit before you and your doctor select bone marrow donation candidates.
Primary outcome measures
- Patient Ancestry Questionnaire [Time frame: Through study completion; an average of 1 year.]
Eligibility criteria
Inclusion criteria
- ≥ 18 years of age.
- Candidate for allogeneic transplantation
Exclusion criteria
1\) Allogeneic stem cell transplantation not medically indicated.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- MD Anderson Cancer Center — Houston
Identifiers
NCT: NCT06450353 · 2024-0253 · NCI-2024-04790