Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Biological samples, Biological.
- Who it may be relevant to
- Registry conditions: Bone Disorder. Basic parameters: up to 99 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Creation of a Biological Collection to Study the Pathophysiology and Identify Predictive Factors for the Evolution of Bone, Calcium and Growth Plate Pathologies
Overview
The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies. This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression and new therapeutic targets.
Interventions
- Other Biological samples
Blood and urine will be taken in larger quantity - Other Biological
Surgical residues may be preserved in the event of surgery carried out as part of the treatment.
Primary outcome measures
- Building a collection of biological samples and clinical-biological data from patients presenting bone, calcium and growth plate pathologies [Time frame: Day 0 and through study completion, an average of 5 years]
Secondary outcome measures (1)
- Identification of potential markers of disease progression based on new knowledge. [Time frame: Day 0 and through study completion, an average of 5 years]
Eligibility criteria
Inclusion criteria
- Children (from birth) with growth plate or bone pathology
- Patients affiliated to or benefiting from a social security scheme
- Patients able to receive information about the study and to understand the information form in order to participate in the study. This implies :
- mastery of the French language
- Not being subject to a restriction of rights by the judicial authorities
- Patients or legal representatives having given their consent to participate in the study (expression of non-opposition).
Exclusion criteria
- Patients under legal protection (guardianship, curatorship or safeguard of justice)
- Pregnant or breast-feeding women
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- University Toulouse Hospital — Toulouse
Identifiers
NCT: NCT06444503 · RC31/24/0214