Protein Requirements Amongst Male Masters-Level Athletes Following a Cycling Exercise Bout as Determined by the Indicator Amino Acid Oxidation Technique
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Amino Acid Intake.
- Who it may be relevant to
- Registry conditions: Healthy, Increased Metabolic Requirements, Dietary Reference Intakes. Basic parameters: from 65 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Canada
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Masters level cyclists are a population above the age of 35 years who frequently participate in prolonged as well as heavy-volume training. Like most endurance-trained athletes, a greater recommended dietary allowance (RDA) for protein of 1.2-1.4 g/kg/bw is suggested. Dietary protein intake is vital for maximizing the benefits of training and ensuring optimal recovery. Dietary recommendations traditionally have been determined through nitrogen balance techniques, however, recent research indicates how this method is potentially underestimating protein requirements. Therefore, there is a need to reassess current dietary recommendations in order to meet the demands of physical activity for highly active populations. Recent efforts to understand protein requirements during rest and following exercise have been completed using the indicator amino acid technique (IAAO). This non-invasive method is reported to provide a robust measure of protein requirements. However, there is limited work in older (≥60 years) active populations. The purpose of this study is to measure the protein requirements in master cyclists, following an endurance training session, using the non-invasive IAAO technique.
Interventions
- Dietary supplement Amino Acid Intake
Amino acid intakes will vary between 0.2 to 2.8 g/kg/d
Primary outcome measures
- 13CO2 Excretion [Time frame: 7-weeks]
Secondary outcome measures (1)
- L[13C]phenylalanine Oxidation [Time frame: 7-weeks]
Eligibility criteria
Inclusion criteria
- 18.5< BMI <35 kg/m\^2
- Overtly healthy masters level cyclists ≥65 years
- Masters level cyclist training (>4 days per week; \~100 km per week)
- Body mass stable over previous 6-months
- Availability for multiple metabolic trials (\~7 trials)
- Ability to travel to and from laboratory facility
Exclusion criteria
- Recent history of weight loss or weight gain (>5% body weight)
- Uncontrolled hypertension
- ≥2 chronic diseases (e.g. diabetes, osteoporosis, dyslipidemia)
- Acute illness that could affect protein metabolism (HIV, renal dysfunction, influenza)
- Currently using anti-inflammatory medications
- Inability to adhere to study protocol (i.e., alcohol, caffeine, dietary restrictions)
- Regular tobacco user
- Illicit drug use
- Habitually ingesting ≥3 g/kg/bw
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Basic science
Study locations
Canada · 1 center
- McGill University — Montreal
Identifiers
NCT: NCT06431334 · A06-M25-23A