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Recruiting NCT06430346

Exercise Prehabilitation for Locoregional Esophageal Cancer

No phase Interventional Esophageal Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Exercise.
Who it may be relevant to
Registry conditions: Esophageal Cancer. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Exercise Prehabilitation for Locoregional Esophageal Cancer: A Pilot Study

Overview

The purpose of the study is to examine the feasibility and acceptability of exercise "prehabilitation" for patients preparing for esophageal cancer resection (removal).

Interventions

  • Behavioral Exercise
    Physical activity and resistance training

Primary outcome measures

  • Retention [Time frame: Up to 11 weeks]
Secondary outcome measures (2)
  • Exploratory outcomes and changes [Time frame: Up to 17 weeks]
  • Clinical and treatment outcomes [Time frame: Up to 17 weeks]

Eligibility criteria

Inclusion criteria

  • Biopsy-proven locoregional esophageal cancer (LEC)
  • Eastern Cooperative Oncology Group (ECOG) performance status 0-2
  • Treatment plan including neoadjuvant chemoradiation therapy and surgical resection
  • Ability to read and speak English

Exclusion criteria

  • Regular engagement in resistance training (2x/week targeting all major muscle groups)
  • Screen failure for exercise safety based on PAR-Q
  • Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease
  • Recent fracture or acute musculoskeletal injury that precludes ability to participate in resistance training safely
  • Numeric pain rating scale of 7 or more out of 10
  • Myopathic or rheumatologic disease that impacts physical function

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Supportive care

Study locations

United States · 1 center
  • Moffitt Cancer Center — Tampa

Identifiers

NCT: NCT06430346 · MCC-23121

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗