Long Term Effect of AIT in Children
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Allergen Immunotherapy Extract.
- Who it may be relevant to
- Registry conditions: Allergy in Children. Basic parameters: 4 years — 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Denmark
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The present study will investigate the long term effect of allergen immunotherapy in a real-life study in children with allergy undergoing subcutaneous or sublingual immunotherapy with grass pollen, birch, house dust mites or venom.
Detailed description
The study will include children aged 5- 18 years who are treated with immunotherapy at Hans Christian Andersen Children' Hospital, Odense University Hospital.
Informed consent to be registered in a database and to receive a questionnaire 5 and 10 years after end of treatment are obtained before start of immunotherapy.
Base line data include information from the patient record: symptoms, medication, blood test and skin prick test results. During treatment effect, medication use, lung function and adverse events are monitored systematically once a year.
The questionnaires 5 and 10 years after end of treatment will focus on allergy symptoms, use of medication and asthma symptoms.
Interventions
- Drug Allergen Immunotherapy Extract
Patients will be treated as usual. The study is an observation of the long term effect of the treatment
Primary outcome measures
- Effect of immunotherapy 5 years after end of treatment [Time frame: 5 years]
Secondary outcome measures (1)
- Effect of immunotherapy 10 years after end of treatment [Time frame: 10 years]
Eligibility criteria
Inclusion Criteria: treated with allergen immunotherapy at HCA Children'sHospital, Odense University Hospital -
Exclusion Criteria: received less than 12 months of treatment with allergen immunotherapy
\-
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Denmark · 2 centers
- Hans Christian Andersen Children's Hospital — Odense
- Hans Christian Andersen Children's Hospital — Odense
Identifiers
NCT: NCT06421415 · HCA-AIT