Recruiting NCT06414083
Histologic Comparison of Ablative Techniques for Endometriosis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Diathermy, CO2 Laser, Argon Beam Coagulator.
- Who it may be relevant to
- Registry conditions: Endometriosis, Endometriosis-related Pain, Endometriosis Pelvic, Endometriosis; Peritoneum. Basic parameters: from 18 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Histologic Comparison of Ablative Techniques for Endometriosis - a Randomized Trial
Overview
To our knowledge, no other human studies directly compare the effectiveness of the various ablative technologies. We set out to design a study to directly compare ablative energy sources and evaluate their ability to destroy native endometriosis tissue in humans.
Interventions
- Device Diathermy
Diathermy will be used to ablate the randomized sample. - Device CO2 Laser
CO2 Laser will be used to ablate the randomized sample. - Device Argon Beam Coagulator
Argon Beam Coagulator will be used to ablate the randomized sample.
Primary outcome measures
- Positive Histology [Time frame: 0 days]
Secondary outcome measures (1)
- Pelvic Pain [Time frame: 3 months]
Eligibility criteria
Inclusion criteria
- Adult women 18 years of age or older
- Already planning to undergo scheduled robotic assisted or laparoscopic excision of lesions for pelvic pain symptoms (pelvic pain, dysmenorrhea, dyspareunia, dysuria, dyschezia, ovarian pain) or endometriosis of any kind (endometriosis of any location, or endometrioma)
Exclusion criteria
- Known pregnancy at enrollment or at the time of the excision surgery
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
United States · 1 center
- Good Samaritan Hospital — Cincinnati
Publications
- Namaky DD, Carrel-Lammert M, Hoehn J, Yeung J. Histologic Comparison of Ablative Techniques for Endometriosis: A Randomized Trial. J Minim Invasive Gynecol. 2026 Jan 10:S1553-4650(26)00044-0. doi: 10.1016/j.jmig.2026.01.020. Online ahead of print. PMID 41525928
Identifiers
NCT: NCT06414083 · 24-007