Menu
Not yet recruiting NCT06381609

Peer Support in Alcohol Dependence

No phase Interventional Alcohol Use Disorder

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Quality life questionnaire AQoLS, Quality life questionnaire Euroqol EQ-5D-5L, Peer support consultations.
Who it may be relevant to
Registry conditions: Alcohol Use Disorder. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Contribution of Addiction Peer Support on Adherence to Care and Clinical Outcomes in Alcohol Dependence: a Prospective Controlled Trial With Medico-economic Component

Overview

Alcohol use disorder (AUD) affects between 4% and 6% of French adults, and requires appropriate medical treatment. However, 20-40% of patients with AUD are lost to follow-up at an early stage. Consequently, it is important for addiction departments to implement and evaluate innovative tools and interventions, including the involvement of peer support, to help patients remain in care, and to assess whether peer support has a positive impact on their clinical outcome. Addiction peer support specialists (APSSs) are individuals who have personally experienced addiction, and who have decided to use their experience to assist other people going through a similar situation, after completing a specific official graduation. Compared to other caregivers, APSSs may induce in patients a sense of identification which could improve the patient motivation to engage and remain in care. This is the main hypothesis and the main scientific objective of the PEERSIAD study, which will aim to confirm that accompanying patients with AUD using APSSs after alcohol detoxification, reduces the rate of lost-to-follow-up and improves the overall clinical outcome.

Interventions

  • Behavioral Quality life questionnaire AQoLS
    Quality life questionnaire AQoLS will be completed by patients of both arms at inclusion, three and six months after inclusion
  • Behavioral Quality life questionnaire Euroqol EQ-5D-5L
    Quality life questionnaire Euroqol EQ-5D-5L will be completed by patients of both arms at inclusion, three and six months after inclusion
  • Other Peer support consultations
    For patients included in the Peer support group, eight mandatory consultations with a peer support specialist will be performed between the inclusion visit and during the three following months. Patients can request additional consultations with the peer support specialist during the 6 first months of follow-up

Primary outcome measures

  • Unplanned cessation of care at 6 months [Time frame: At 6 months after inclusion]
Secondary outcome measures (12)
  • Number of unfulfilled consultations [Time frame: 6 months after inclusion]
  • Euroqol-5D-5L questionnaire score [Time frame: At inclusion, 3 and 6 months after inclusion]
  • Difference in costs (in euros) [Time frame: At 1, 2 and 3 years after the beginning of implementation on French territory]
  • Number of AUD criteria according to Diagnostic and Statistical Manual of Mental Disorders (DSM-5) [Time frame: At inclusion, 3 and 6 months after inclusion]
  • Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) score [Time frame: At inclusion, 3 and 6 months after inclusion]
  • average number of standard drinks declared per week [Time frame: At inclusion, 3 and 6 months after inclusion]
  • Alcohol Quality of Life Scale (AQoLS) score [Time frame: At inclusion, 3 and 6 months after inclusion]
  • State-Trait Anxiety Inventory (STAI-Y) score [Time frame: At inclusion, 3 and 6 months after inclusion]
  • Montgomery-Åsberg Depression Rating Scale (MADRS) score [Time frame: At inclusion, 3 and 6 months after inclusion]
  • Cannabis Use Disorders Identification Test - Revised (CUDIT-R) score [Time frame: At inclusion, 3 and 6 months after inclusion]
  • type of opioid use [Time frame: At inclusion, 3 and 6 months after inclusion]
  • frequency of opioid use [Time frame: At inclusion, 3 and 6 months after inclusion]

Eligibility criteria

Inclusion criteria

  • Aged ≥ 18
  • Socially insured
  • Meeting DSM-5 criteria for alcohol use disorder (AUD)
  • Abstinent from alcohol and involved in supervised alcohol withdrawal for at least 5 days and no more than 21 days (outpatient or inpatient)
  • Starting a post-detoxification outpatient program

Exclusion criteria

  • Other severe substance use disorder, i.e. DSM-5 criteria ≥ 6 (excluding tobacco)
  • Patient under protective measure (safeguard measure, guardianship) or deprived of liberty or in ordered care and hospitalization measures without consent.
  • Inability to communicate and express oneself orally in French, compromising the possibility of exchanges between the Peer support and the patient.
  • Psychiatric or cognitive comorbidities making inclusion impossible, at the investigator's discretion.
  • Individual accompaniment by a Peer support in the 15 days prior to inclusion.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Health services research

Study locations

France · 5 centers
  • CH Le Vinatier — Bron
  • Hôpital Beaujon — Clichy
  • GH Nord, Hospices Civils de Lyon — Lyon
  • CHS St Anne — Paris
  • Bichat Hospital — Paris

Identifiers

NCT: NCT06381609 · 69HCL22_0901

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗