Preventive Interventions for Chronic Pain Worsening
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Virtual Reality-based Pain Self-management program.
- Who it may be relevant to
- Registry conditions: Chronic Non-Cancer Pain. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Denmark
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This is an open label randomized controlled trial (RCT), which will be conducted with patients of the Copenhagen Wound Healing Center at Bispebjerg Hospital in Copenhagen (DK). The trial has two arms (1:1): A Virtual Reality based Pain Self-management (VRPS) program group, and a control group (usual care). Included will be 44 patients at least 18 years old; fluent in the Danish language; complaint of pain lasting 3 months or more; in average pain intensity score ≥ 3 (numerical rating scale 0 to 10); access to internet; and willing and available to participate in the study. Excluded will be specialized or multidisciplinary pain treatment at baseline; history of epilepsy, seizure disorder, nausea or dizziness, hypersensitivity to flashing light or motion or other diseases that may prevent use of virtual reality equipment; injury to eyes, face or neck.
Detailed description
Considering the need of interventions to improve pain self-management to interrupt the "pain chronification" process and the indications regarding advantages of cognitive behavioral techniques and technologic resources, the purpose of this study is to test a homebased intervention connecting these areas. Here, the effects of a non-pharmacological technique delivered through a virtual reality-based pain self-management program will be tested in patients with non-cancer pain lasting three months or more. The intervention target primarily pain relief by providing pain regulating strategies.
The investigators will test the main hypothesis that participants assigned Virtual Reality-based Pain Self-management program (VRPS) present reduction of pain intensity among other outcomes at 2 months post-intervention as well as after 6-, 9-, and 12-months follow-up when compared to treatment as usual (control group).The primary aim is to investigate the effects of VRPS on worst pain intensity in the last 24h in patients with non-cancer pain lasting 3 months or more at 2 months post-intervention.The secondary aims are to analyze the effects of the intervention on other patient-reported outcomes measures (PROMs), which are pain intensity at follow-ups, pain interference in daily activities, pain catastrophizing, pain acceptance, health-related quality of life, anxiety, depression, perceived change on over-all pain status, use of analgesic medication, and use of health care system among patients with non-cancer pain lasting 3 months or more.
Interventions
- Device Virtual Reality-based Pain Self-management program
The VRPS has a variety of modules that can be used for pain management. For this project we have selected relaxation, mindful escapes, pain distraction games, and dynamic breathing modules. All modules were designed to minimize triggers of emotional distress or cybersickness.
Primary outcome measures
- Pain intensity [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
Secondary outcome measures (10)
- Pain intensity and interference in daily activities [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Pain catastrophizing [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Pain acceptance [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Health status [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Health related quality of life [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Anxiety [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Depression [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Use of medication [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Use of healthcare system [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
- Number of absent days at work [Time frame: At baseline, 2 months, 6 months, 9 months and 12 months after intervention]
Eligibility criteria
Inclusion criteria
- At least 18 years old
- Fluent in the Danish language
- Complaint of pain lasting 3 months or more; in average pain intensity score ≥ 3 (numerical rating scale 0 to 10)
- Access to internet
- Willing and available to participate in the study.
Exclusion criteria
- Specialized or multidisciplinary pain treatment at baseline
- History of epilepsy
- Seizure disorder
- History of nausea or dizziness
- Hypersensitivity to flashing light or motion or other diseases that may prevent use of virtual reality equipment.
- Injury to eyes, face or neck that impedes comfortable use of virtual reality equipment.
- Current cancer disease
- Medical diagnosis of depression
- Cognitive dysfunction that interferers with compliance to the study,
- Currently pregnant or planning to become pregnant during the study period
- No access to the internet during the study period.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Factorial
- Masking
- Open label
- Primary purpose
- Prevention
Study locations
Denmark · 1 center
- Rigshospitalet — Copenhagen
Identifiers
NCT: NCT06351046 · NCT05178082_WP3