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Recruiting NCT06335524

Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants

No phase Interventional Child Development Infant Development Infant, Premature, Diseases

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Finger puppet, Bookworm reading intervention training and routine EDI care..
Who it may be relevant to
Registry conditions: Child Development, Infant Development, Infant, Premature, Diseases. Basic parameters: 1 Week — 17 Weeks · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants: A Randomized Clinical Trial

Overview

This study will test the hypothesis that in preterm infants a caregiver-implemented early developmental intervention (EDI) using finger puppets to develop joint attention and encourage interactive communication with routine EDI care including Bookworm training compared with routine EDI care including Bookworm training alone will increase the Ages and Stages Questionnaire® score at 12 months corrected age.

Interventions

  • Behavioral Finger puppet
    The intervention group will receive finger-puppets and additional training pertaining to infant parent interaction and developmentally appropriate infant communication training.
  • Behavioral Bookworm reading intervention training and routine EDI care.
    Routine EDI care including Bookworm training.

Primary outcome measures

  • ASQ-3 scores [Time frame: 12 months corrected age]
Secondary outcome measures (12)
  • ASQ-3 scores [Time frame: 24 months corrected age]
  • ASQ scores below -2SD [Time frame: 12 months corrected age]
  • ASQ scores below -2SD [Time frame: 24 months corrected age]
  • ASQ scores below -1SD [Time frame: 12 months corrected age]
  • ASQ scores below -1SD [Time frame: 24 months corrected age]
  • ASQ-SE2 scores [Time frame: 12 months corrected age]
  • ASQ-SE2 scores [Time frame: 24 months corrected age]
  • Severe neurodevelopmental impairment [Time frame: 24 months corrected age]
  • Moderate or severe neurodevelopmental impairment [Time frame: 24 months corrected age]
  • Cognitive Composite Score on BSID-IV [Time frame: 24 months corrected age]
  • Language Composite Score on BSID-IV [Time frame: 24 months corrected age]
  • Motor Composite Score on BSID-IV [Time frame: 24 months corrected age]

Eligibility criteria

Inclusion criteria

  • inborn at UAB, delivered at less than 34 weeks' gestation, 32-39 weeks' PMA, off sedatives, and off invasive respiratory support.

Exclusion criteria

  • a major malformation, a known syndrome, enrolled in a competing trial targeting neurodevelopmental outcomes as a primary outcome.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

United States · 1 center
  • University of Alabama at Birmingham — Birmingham

Identifiers

NCT: NCT06335524 · IRB-300012718 · UAB

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗