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Recruiting NCT06334601

Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness

— Observational Obstructive Sleep Apnea

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Tests of upper airway collapsibility and muscle responsiveness..
Who it may be relevant to
Registry conditions: Obstructive Sleep Apnea. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Diurnal Evaluation of Obstructive Sleep Apnea (OSA) Upper Airway Collapsibility and Muscle Responsiveness

Overview

In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness.

Interventions

  • Diagnostic test Tests of upper airway collapsibility and muscle responsiveness.
    Upper airway collapsibility, upper airway muscle responsiveness and loop gain will be assessed during single study visit. Polysomnography

Primary outcome measures

  • Upper airway collapsibility [Time frame: During the diagnostic test]
  • Upper airway muscle responsiveness [Time frame: During the diagnostic test]

Eligibility criteria

Inclusion criteria

  • Obstructive Sleep Apnea (OSA)
  • At home-polygraphy with at least one EEG channel (PSG) reporting moderate-to severe obstructive sleep apnea (apnea-hypopnea index >14).

Exclusion criteria

  • OSA treatment ongoing during two weeks before PSG
  • Unstable cardio-respiratory disease in the 3 months before enrollment
  • Subjects in O2 treatment

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

Italy · 1 center
  • IRCCS Istituto Auxologico Italiano,Ospedale San Luca — Milan

Identifiers

NCT: NCT06334601 · 09C333

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗