Menu
Recruiting NCT06330467

Prevalence of Dissociative Identity Disorder in At-risk Outpatient Groups Reporting Childhood Trauma.

No phase Interventional Dissociative Disorder

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: psychometric assessment, semi-structured clinical interview.
Who it may be relevant to
Registry conditions: Dissociative Disorder. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The investigators will study the prevalence of dissociative identity disorder (DID) in three populations at risk in cases of childhood psychotrauma : patients with a diagnosis of borderline personality, patients with a diagnosis of functional dissociative crises (FDC) and patients with early psychosis. The investigators will also study the prevalence of other dissociative disorders and the frequency of complex post-traumatic stress disorder. The investigators will also look for correlations between the type of maltreatment in childhood, the age of onset of trauma and the type of diagnosis of dissociative disorders. The investigators hope to include 150 borderline patients, 150 FDC patients and 50 early psychosis patients. Data collection will be done via a psychometric administration of 7 self-completion questionnaires as well as the completion of the SCID-D semi-structured interview.

Interventions

  • Diagnostic test psychometric assessment
    Psychometric testing to assess trauma and dissociative disorders, and in particular dissociative identity disorder.
  • Diagnostic test semi-structured clinical interview
    Semi-structured interview for the assessment of dissociative disorders (SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders)

Primary outcome measures

  • SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders / DSM = Diagnostic and Statistical Manual of Mental Disorders / ICD = International Classification of Diseases [Time frame: Inclusion visit]
Secondary outcome measures (8)
  • SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders [Time frame: Inclusion visit]
  • CTQ-28 : Childhood Trauma Questionnaire [Time frame: Inclusion visit]
  • life events inventory DSM-5 [Time frame: Inclusion visit]
  • PCL-5 : Posttraumatic stress disorder CheckList-5 [Time frame: Inclusion visit]
  • ITQ : International Trauma Questionnaire [Time frame: Inclusion visit]
  • SDQ-20 : Somatoform Dissociative questionnaire [Time frame: Inclusion visit]
  • DIS-Q : Dissociation Questionnaire [Time frame: Inclusion visit]
  • DES : Dissociative Experience Scale [Time frame: Inclusion visit]

Eligibility criteria

I - Inclusion Criteria:

I-1: For all groups:

  • Male or female
  • Age > or = 18
  • Enrolled in or benefiting from a social security scheme
  • Patient fluent in French
  • Patient willing to undergo a psychological evaluation between 1h30 and 3h30
  • Patient with a known history of psychotrauma in childhood before the age of 18 (sexual abuse, mistreatment, school harassment, natural disasters, attacks, etc.).
  • Patient having received and understood complete information on the organization of the research and having given written free and informed consent prior to participation in the study.

I-2 : Patients in the borderline group

  • Patients with main diagnosis of emotionally labile personality
  • Patients with at least one psychiatric hospitalization in the last 3 years

I-3 : Patients in the early psychosis group

Patient with a diagnosis of mental state at risk of psychosis according to the criteria defined by CAARMS (Comprehensive Assessment of At Risk Mental State) OR Patients diagnosed with a first psychotic episode on an outpatient basis or following a hospital stay

I-4 : Patients in the functional dissociative crises group

Patients diagnosed with functional dissociative crises by a specialized epileptologist

II- Non-inclusion criteria

  • Impairment of the subject making it difficult or not impossible to participate in the trial or to understand the information provided to him/her
  • Patients with specific difficulties in understanding SCID-D questions
  • Psychiatric condition requiring hospitalization
  • Patients with symptoms of recent toxic consumption (alcohol, cannabis, other ...) disrupting assessment responses
  • Patient taking part in a pharmacological study involving a pro-dissociative molecule of the psychedelic type
  • Pregnant, parturient or nursing mothers
  • Person deprived of liberty by judicial or administrative decision
  • Person in a life-threatening emergency
  • An adult under legal protection (guardianship, curatorship, safeguard of justice)
  • Person unable to give consent and not subject to a legal protection measure

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Diagnostic

Study locations

France · 3 centers
  • Centre Psychothérapique de Nancy - CLIP — Nancy
  • Centre Psychothérapique de Nancy - CMP Jacquard et Des Près — Nancy
  • CHRU Nancy - Neurology department — Nancy

Identifiers

NCT: NCT06330467 · 2023-A02442-43 · RIPH 2023-02

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗