Not yet recruiting NCT06330155
A Genetic Study for Alzheimer Dementia: Case-control Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Alzheimer Dementia (AD). Basic parameters: from 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The purpose of this study is to find out the difference in genetic test results between Alzheimer's dementia patients and healthy subjects. The investigators want to identify genes that are importantly related to Alzheimer's dementia.
Primary outcome measures
- genetic analysis [Time frame: Baseline]
Secondary outcome measures (3)
- Measurement of Korean version of mini-mental state examination (K-MMSE) [Time frame: screening, Baseline]
- Measurement of Clinical Dementia Rating (CDR) [Time frame: screening, Baseline]
- Measurement of Geriatric Depression Scale (GDSd) [Time frame: Baseline]
Eligibility criteria
- Inclusion Criteria: Alzheimer's dementia patient
- Adult patients over 60 years old
- Patients with a Alzheimer's dementia patient
- Total Korean version of mini-mental state examination (K-MMSE) score less than 24
- Total Clinical Dementia Rating (CDR) over 0.5
- Inclusion Criteria: healthy subjects
- Adult healthy over 60 years old
- Total Korean version of mini-mental state examination (K-MMSE) over 24
- Total Clinical Dementia Rating (CDR) is 0
- Exclusion Criteria:
- Those with severe medical conditions such as unstable conditions of the cardiovascular system, digestive system, respiratory system, endocrine system, etc., who are in poor general condition
- In the case of a person with impaired consent (MMSE less than 10 points), if not accompanied by a guardian
- Other cases where the researcher determines that participation in this clinical trial is not appropriate (Patients who are participating in other studies or have participated in other studies within the past 30 days can also participate in this study.)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06330155 · 2024-01-032