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Recruiting NCT06320288

Analysis of Trunk and Center of Mass Control Development During Gait in Children With Cerebral Palsy (VERTEBRAL)

Observational Children With Cerebral Palsy

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Children With Cerebral Palsy. Basic parameters: 18 months — 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Analysis of Trunk and Center of Mass Control Development During Gait in Children With Cerebral Palsy

Overview

During the acquisition of posturokinetic abilities such as walking, postural control of the trunk is of paramount importance. Indeed, its development is strongly linked to the overall motor function of children. In cerebral palsy (CP), a term that refers to a set of motor disorders following a perinatal lesion, deficits in axial control are present from early childhood. These deficits are strongly correlated with the functional deficits observed in this population. In particular, during walking, deviations of the trunk (amplitudes, accelerations) are observed in the three planes of space. While recent literature increasingly questions the impact of trunk control deficit on the walking of children with CP, elements are still missing for a holistic understanding of the interaction between locomotor and postural disorders in children with CP. In particular, no study has focused on the deviations of trunk control and the center of mass (which is a global indicator of balance strategies) during the development and maturation of walking in children with CP. Therefore, the primary objective of this cross-sectional observational study will be to characterize the development of trunk control and center of mass during walking in children with CP.

Primary outcome measures

  • Trunk and center-of-mass accelerations and acceleration variability [Time frame: At the end of the one-day experimental]
Secondary outcome measures (3)
  • Gait Variability Index [Time frame: At the beginning of the one-day experimental]
  • Trunk Control Measurement Scale score (TCMS) [Time frame: At the beginning of the one-day experimental]
  • Early Clinical Assessment of Balance score [Time frame: At the beginning of the one-day experimental]

Eligibility criteria

Inclusion criteria

  • Children (< 18 years) with cerebral palsy
  • GMFCS I to III
  • Independent walking with or without technical walking aids (walker, crutches, etc.)
  • Able to understand the instructions of various clinical assessments and functional explorations
  • Affiliated with a social security scheme

Exclusion criteria

Children with cerebral palsy

  • Neuro-orthopaedic surgery of the lower limbs or trunk within the last 12 months
  • Botulinum toxin A injections within the last 6 months
  • Therapeutic intervention targeting trunk control last 6 months

Typically developing children

  • Surgery on lower limbs or trunk last 12 months
  • Neurological and/or orthopedic pathology that may influence gait

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

France · 1 center
  • Institut Régional de Médecine Physique et de Réadaptation — Nancy

Identifiers

NCT: NCT06320288 · 2023-A00505-40

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗