The Clinical Outcomes and Prediction of Thermal Ablation for Low-risk Papillary Thyroid Carcinoma
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: thyroid surgery, ultrasound-guided thermal ablation.
- Who it may be relevant to
- Registry conditions: Papillary Thyroid Cancer. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Clinical Outcomes and Artificial Intelligence Prediction Model of Ultrasound-guided Thermal Ablation for the Treatment of Low-risk Papillary Thyroid Carcinoma
Overview
1. To evaluate the clinical outcomes of ultrasound-guided thermal ablation and thyroid surgery for the treatment of papillary thyroid carcinoma; 2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of papillary thyroid carcinoma;
Interventions
- Procedure thyroid surgery
thyroid lobectomy - Procedure ultrasound-guided thermal ablation
radiofrequency ablation; microwave ablation or laser ablation
Primary outcome measures
- rate of disease progression [Time frame: more than 5 year]
Secondary outcome measures (2)
- Rate of complications [Time frame: 1week]
- Rate of tumor disappearance [Time frame: 2 year]
Eligibility criteria
Inclusion criteria
- patients age between 18 and 80 year old, both sex
- papillary thyroid carcinoma confirmed by core-needle biopsy or fine-needle aspiration
- the largest diameter ≤2.0 cm
- no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, nech and chest CT
- follow-up period ≥12 months,
Exclusion criteria
- patients with convincing evidence of aggressive papillary thyroid carcinoma or other type of thyroid cancer by biopsy
- history of neck radiation
- history of thyroid surgery
- coagulation disorder
- serious heart, respiratory, liver, or renal failure
- dysfunction of the vocal cord on the opposite side
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Chinese PLA General Hospital — Beijing
Identifiers
NCT: NCT06316895 · S2023-706