Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Non-Interventional Study.
- Who it may be relevant to
- Registry conditions: Prostate Neoplasm. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study evaluates if technical improvements in MRI can be used to provide improved performance contrast-enhanced MRI as used for angiography and perfusion as well as in non-contrast MRI.
Detailed description
PRIMARY OBJECTIVE:
I. To study how a variety of technological approaches in MRI can be used to provide improved performance contrast-enhanced MR imaging as used for angiography and perfusion as well as in MR image acquisition without the use of contrast material.
OUTLINE: This is an observational study.
Participants undergo a non-contrast MRI on study and may optionally undergo a second non-contrast MRI on study. Participants may also undergo blood sample collection on study.
Interventions
- Other Non-Interventional Study
Non-interventional study
Primary outcome measures
- Improved performance in contrast-enhanced magnetic resonance imaging (MRI) as used for angiography and perfusion [Time frame: Baseline (at enrollment); possible second scan at a later date]
Eligibility criteria
Inclusion criteria
- Adults
Exclusion criteria
- Standard exclusion criteria for clinical MRI; e.g. cardiac pacemaker, claustrophobia, an implanted device that has been determined to be MR conditional at 1.5T but not at 3T, anticipated considerable susceptibility artifact from hip prosthesis, etc.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United States · 2 centers
- Mayo Clinic in Arizona — Scottsdale
- Mayo Clinic in Rochester — Rochester
Identifiers
NCT: NCT06315595 · 15-003511 · R01EB031790 · R01CA283663 · R21CA277138 · W81XWH-15-1-0341