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Recruiting NCT06301438

Dalpiciclib in HR+/HER2- ABC

Observational Advanced Breast Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: dalpiciclib.
Who it may be relevant to
Registry conditions: Advanced Breast Cancer. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Efficacy and Safety of Dalpiciclib in HR+/HER2- Advanced Breast Cancer: a Real-world Study

Overview

To evaluate the efficacy and safety of dalpiciclib in patients with HR-positive/HER2-positive advanced breast cancer.

Interventions

  • Drug dalpiciclib
    dalpiciclib oral day 1-21, every 28 days

Primary outcome measures

  • Progression-Free Survival [Time frame: From the date of starting dalpiciclib to the date of first documentation of progression or death (up to approximately 1 years)]
Secondary outcome measures (1)
  • Adverse events [Time frame: From the date of starting dalpiciclib to the end of the treatment (up to approximately 1 year)]

Eligibility criteria

Inclusion criteria

  • Histologically confirmed advanced breast cancer
  • Hormone receptor-positive and human epidermal growth factor receptor 2-negative
  • ECOG 0-1

Exclusion criteria

  • Pregnant or breastfeeding
  • History of immunodeficiency

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Renji Hospital, School of Medicine, Shanghai Jiaotong University — Shanghai

Identifiers

NCT: NCT06301438 · LY2024-022-A

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗