De Quervain's Disease in the Acute Phase:a Study Aimed at Evaluating the Effectiveness of Standard Physiotherapy Treatment (HANDGUIDE), Compared to Experimental Treatment After Performing Ultrasound-guided Infiltrative Therapy.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Rehabilitation, Standard.
- Who it may be relevant to
- Registry conditions: De Quervain Disease, Hand Tenosynovitis. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
De Quervain's Disease in the Acute Phase: Randomized Interventional Study Aimed at Evaluating the Effectiveness of Standard Physiotherapy Treatment (HANDGUIDE), Compared to Experimental Treatment After Performing Ultrasound-guided Infiltrative Therapy.
Overview
The objective of the study is to compare pain reduction and disability reduction in two groups of patients diagnosed with de Quervain syndrome who will undergo ultrasound-guided infiltrative treatment with corticosteroid as per normal clinical practice: * the control group will subsequently be subjected to a standard treatment based on the European guidelines of the HANDGUIDE group, * the experimental group will subsequently carry out a program of eccentric exercises.
Interventions
- Other Rehabilitation
-the experimental group will carry out a program of eccentric exercises following the infiltration and will also wear the wrist brace for 4 weeks. - Other Standard
-the standard group will carry out a program of generic exercises following the infiltration and will also wear the wrist brace for 4 weeks.
Primary outcome measures
- Numeric Pain Rating Scale [Time frame: At baseline (day 0)]
- Numeric Pain Rating Scale [Time frame: After 1 month]
- Numeric Pain Rating Scale [Time frame: After 3 months]
- Numeric Pain Rating Scale [Time frame: After 6 months]
Secondary outcome measures (8)
- Disabilities of Arm, Shoulder and Hand [Time frame: At baseline (day 0)]
- Disabilities of Arm, Shoulder and Hand [Time frame: After 1 month]
- Disabilities of Arm, Shoulder and Hand [Time frame: After 3 months]
- Disabilities of Arm, Shoulder and Hand [Time frame: After 6 months]
- Patient-Rated Wrist Evaluation [Time frame: At baseline (day 0)]
- Patient-Rated Wrist Evaluation [Time frame: After 1 month]
- Patient-Rated Wrist Evaluation [Time frame: After 3 months]
- Patient-Rated Wrist Evaluation [Time frame: After 6 months]
Eligibility criteria
Inclusion criteria
- Patients of both sexes with a minimum age of 18 years;
- Medical diagnosis of de Quervain syndrome assessed through orthopedic clinical examination e confirmation by ultrasound;
- Signing of the informed consent and participation in the study.
Exclusion criteria
- Patients who are not self-sufficient or not able to understand and want;
- Presence of other pathologies in the hand affected by de Quervain pathology, such as intersection syndrome, neuropathies, fractures, rhizoarthrosis, arthrosis of the radio-carpal or intercarpal joint, intercarpal instability, cervical radiculopathy, rheumatic or metabolic pathologies;
- Pregnant or breastfeeding women.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Italy · 1 center
- Istituto Ortopedico Rizzoli — Bologna
Publications
- Wolf JM, Sturdivant RX, Owens BD. Incidence of de Quervain's tenosynovitis in a young, active population. J Hand Surg Am. 2009 Jan;34(1):112-5. doi: 10.1016/j.jhsa.2008.08.020. Epub 2008 Dec 10. PMID 19081683
- Walker-Bone K, Palmer KT, Reading I, Coggon D, Cooper C. Prevalence and impact of musculoskeletal disorders of the upper limb in the general population. Arthritis Rheum. 2004 Aug 15;51(4):642-51. doi: 10.1002/art.20535. PMID 15334439
- Ferrara PE, Codazza S, Cerulli S, Maccauro G, Ferriero G, Ronconi G. Physical modalities for the conservative treatment of wrist and hand's tenosynovitis: A systematic review. Semin Arthritis Rheum. 2020 Dec;50(6):1280-1290. doi: 10.1016/j.semarthrit.2020.08.006. Epub 2020 Aug 29. PMID 33065423
Identifiers
NCT: NCT06296472 · MDQ23