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Recruiting NCT06290167

A New 360° Dual-task Based Protocol for the Pre-clinical In-hospital and At-home Rehabilitation of Elderly: DUAL-Rehab

No phase Interventional Cognitive Decline

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: 360° media, Treatment As Usual (TAU), In hospital sessions, at home sessions.
Who it may be relevant to
Registry conditions: Cognitive Decline. Basic parameters: from 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The main objective of this project is two-fold 1. to develop a Dual-Task training exploiting the potentiality of the 360° technology in terms of interactivity and ecological validity 2. to investigate its efficacy in improving the cognitive functioning in a randomized clinical trial for 2 different populations: subjects with subjective memory complaints and mild cognitive impairment. Specifically, participants will follow an integrated training including 2 phases: 1)in-hospital rehabilitation, where subjects will be provided sessions of the training in immersive modality; 2)at-home rehabilitation, where older adults will be asked to perform at home the non-immersive version of the training using a tablet. Expected outcome is an improvement in cognitive functioning (assessed with a complete neuropsychological battery) after the training, thus advancing literature about non-pharmacological interventions in the preclinical stages of dementia along with innovative technical instruments.

Interventions

  • Device 360° media
    sessions with head mounted display in hospital and sessions with tablet at home
  • Other Treatment As Usual (TAU)
    sessions of TAU rehabilitation in hospital and sessions TAU rehabilitation at home
  • Other In hospital sessions
    sessions will be carried out under the supervision of a therapist
  • Other at home sessions
    sessions will be carried out without the supervision of a therapist
  • Other Mild Cognitive Impairment
    half of this group will perform the protocol with 360° videos and the other half will perform the TAU
  • Other Subjective Memory Complain
    half of this group will perform the protocol with 360° videos and the other half will perform the TAU

Primary outcome measures

  • Cognitive functions [Time frame: Immediately after the training experience]
  • Motor functions [Time frame: Immediately after the training experience]

Eligibility criteria

Inclusion Criteria (group of SMC):

  • > 65 years old
  • self-reported memory complaints
  • score on Mini-Mental State Examination greater than or equal to 27/30 (normal range)

Exclusion criteria

  • no evidence of objective impairments on the neuropsychological testing, scores on the Clinical Dementia Rating < 0.5

Inclusion Criteria (group of MCI):

  • > 65 years old
  • a self-reported (or reported by a caregiver) cognitive decline
  • an objective impairment on the neuropsychological testing
  • scores on the Clinical Dementia Rating < 0.5.

Exclusion criteria

  • no dementia

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Factorial
Masking
Double blind
Primary purpose
Treatment

Study locations

Italy · 1 center
  • Istituto Auxologico Italiano IRCCS — Milan

Identifiers

NCT: NCT06290167 · 30M201

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗