Optic Nerve Sheath Diameter in Hypertensive Emergency
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Optic Nerve Sheath Diameter.
- Who it may be relevant to
- Registry conditions: Hypertensive Emergency, Papilledema, Hypertension. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Point-of-care Ultrasound of Optic Nerve Sheath Diameter in Suspected Hypertensive Emergency
Overview
This prospective observational study investigates the potential of point-of-care ultrasonography of the optic nerve sheath diameter (ONSD) to rule out papilledema in patients with suspected hypertensive emergency. The primary focus is on assessing ONSD sensitivity in identifying papilledema (hypertensive retinopathy grade 4), while secondary endpoints include hypertensive retinopathy grade 3, hypertensive encephalopathy, and the need for intravenous rapid-acting medications to lower elevated blood pressure. This study aims to determine the diagnostic characteristics of this procedure for the diagnosis of hypertensive retinopathy, thus assessing its potential as a screening tool to rule out hypertensive retinopathy by the acute internal medicine doctor.
Interventions
- Diagnostic test Optic Nerve Sheath Diameter
Point of care ultrasonography of the optic nerve sheath diameter
Primary outcome measures
- Papilledema [Time frame: 2 years]
Secondary outcome measures (4)
- Hypertensive retinopathy grade 3 & 4 combined [Time frame: 2 years]
- Hypertensive encephalopathy [Time frame: 2 years]
- Rapid acting medications administered intravenously to lower the elevated blood pressure [Time frame: 2 years]
- Presence of a bulging optic nerve disc and/or crescent sign found by ultrasonography of the optic nerve [Time frame: 2 years]
Eligibility criteria
Inclusion criteria
- ≥ 18 years old
- Any patient presenting to the emergency department (ED) with suspected hypertensive emergency i.e.: blood pressure of > 200 millimetres of mercury (mmHg) systolic and/or > 120 mmHg diastolic
Exclusion criteria
- Patients with preexisting optic nerve head changes such as glaucoma, pre-existing retinal artery/vein occlusions or any other condition that makes assessment of the fundi impossible.
- Primary neurological cause of hypertension: ischemic cerebrovascular incident
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06286696 · NL84914.058.23