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Recruiting NCT06283472

Enhancing Prospective Thinking in Early Recovery (BEAM)

No phase Interventional Alcohol Use Disorder

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: High-Intensity Cue, Low-Intensity Cue.
Who it may be relevant to
Registry conditions: Alcohol Use Disorder. Basic parameters: 18 years — 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Enhancing Prospective Thinking in Early Recovery

Overview

The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question\[s\] this trial aims to answer are: * Will high-intensity EFT cues will produce greater delayed reward preference than low-intensity cues? * Will high-intensity EFT cues effect greater treatment-seeking interest? * Will high-intensity EFT cues elicit greater response in regions for prospective thinking during delay discounting (vs. low-intensity) * Will nucleus accumbens-precuneus resting connectivity correlate with behavioral SS? * Will the novel behavioral SS decision-making task activate the nucleus accumbens? Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.

Interventions

  • Behavioral High-Intensity Cue
    Participants in the high-intensity group will receive high-intensity image cues that represent self-reported events they did on the previous day and self-reported events they look forward to in the future.
  • Behavioral Low-Intensity Cue
    Participants in the low-intensity group will receive low-intensity image cues that represent self-reported events they did on the previous day and self-reported events they look forward to in the future.

Primary outcome measures

  • Increase Prospective Thinking [Time frame: Study Day Visit (Day 1)]
  • Delayed Rewards [Time frame: Study Day Visit (Day 1)]

Eligibility criteria

Inclusion criteria

  • Individuals who meet current heavy drinking (≥2 heavy drinking days/month OR ≥7 drinks/week for biological females, and ≥14 drinks/week if biological male \[NIAAA definition\] and/or AUDIT scores ≥8)
  • English comprehension

Exclusion criteria

  • Unstable medical disorders
  • Outside the age range of 18-60
  • Smell/taste disorders
  • Unstable psychiatric conditions

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Supportive care

Study locations

United States · 1 center
  • Indiana University School of Medicine - Goodman Hall — Indianapolis

Identifiers

NCT: NCT06283472 · 1805574553; Aims 14-16 · 2P60AA007611-403343 · 2P60AA007611

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗