Trajectory of Frailty and Cognitive Dysfunction in Older Adults
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: No intervention.
- Who it may be relevant to
- Registry conditions: Frailty, Cognitive Dysfunction, Community-dwelling Older Adults. Basic parameters: from 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Study of the Joint Trajectory of Frailty and Cognitive Dysfunction Among Community-dwelling Older Adults
Overview
To explore the heterogeneity of the development trend of frailty and cognitive function of older adults.
Detailed description
According to the inclusion and exclusion criteria, the older adults will be selected from community health service centers in four districts of Beijing. Frailty and cognitive function of the older adults will be assessed for a 24-month longitudinal multi-time (baseline, 6, 12 and 24 months). The heterogeneity of the development trend of frailty and cognitive function will be explored, and the subgroups of joint development trajectory of frailty and cognitive impairment will be classified, so as to identify high-risk populations that need to be managed.
Interventions
- Other No intervention
No intervention
Primary outcome measures
- Frailty [Time frame: Baseline, 6 month, 12 month, and 24 month]
- Cognitive function [Time frame: Baseline, 6 month, 12 month, and 24 month]
Eligibility criteria
Inclusion criteria
- Age ≥60 years.
- Older adults with clear consciousness, ability of simple written and verbal communication.
- They volunteered to participate in this study, and signed an informed consent.
Exclusion criteria
- A clear diagnosis of any type of dementia.
- There are neurological diseases that clearly lead to cognitive dysfunction, such as severe cerebrovascular disease, brain trauma, intracranial tumors, etc.
- They have been clearly diagnosed with mental disorders affecting cognitive function, including schizophrenia, depression, bipolar disorder, etc.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06276166 · 72374215